Kaposi sarcoma in a child after hematopoietic stem cell transplantation: Should pre‐transplant HHV‐8 screening be considered in recipients from high prevalence areas?
Kaposi sarcoma (KS) is an angioproliferative disease associated with human herpesvirus 8 (HHV‐8). We report the case of a 10‐year‐old male from a high HHV‐8 prevalence area, diagnosed with severe aplastic anemia who underwent an upfront hematopoietic stem cell transplantation (HSCT). Five months aft...
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| Veröffentlicht in: | Transplant infectious disease 2021-06, Vol.23 (3), p.n/a |
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| container_title | Transplant infectious disease |
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| creator | Valero‐Arrese, Lorena Benítez‐Carabante, María Isabel Soques Vallejo, Elena Roca, Isabel Navarro Jiménez, Alexandra Díaz‐de‐Heredia, Cristina |
| description | Kaposi sarcoma (KS) is an angioproliferative disease associated with human herpesvirus 8 (HHV‐8). We report the case of a 10‐year‐old male from a high HHV‐8 prevalence area, diagnosed with severe aplastic anemia who underwent an upfront hematopoietic stem cell transplantation (HSCT). Five months after transplant, the patient was diagnosed with KS with skin, mucosae, lymph nodes and lung involvement. After withdrawal of immunosuppression the patient achieved complete remission without requiring further treatments. KS may occur after HSCT in patients from high HHV‐8 prevalence areas. Considering that, we propose that screening of HHV‐8 by antibody testing could be considered in HSCT donors/recipients from these areas. |
| doi_str_mv | 10.1111/tid.13525 |
| format | Article |
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We report the case of a 10‐year‐old male from a high HHV‐8 prevalence area, diagnosed with severe aplastic anemia who underwent an upfront hematopoietic stem cell transplantation (HSCT). Five months after transplant, the patient was diagnosed with KS with skin, mucosae, lymph nodes and lung involvement. After withdrawal of immunosuppression the patient achieved complete remission without requiring further treatments. KS may occur after HSCT in patients from high HHV‐8 prevalence areas. Considering that, we propose that screening of HHV‐8 by antibody testing could be considered in HSCT donors/recipients from these areas.</description><identifier>ISSN: 1398-2273</identifier><identifier>EISSN: 1399-3062</identifier><identifier>DOI: 10.1111/tid.13525</identifier><language>eng</language><publisher>Malden: Wiley Subscription Services, Inc</publisher><subject>Anemia ; Antibodies ; Aplastic anemia ; children ; Hematopoietic stem cells ; HHV‐8 ; HSCT ; Immunosuppression ; Kaposi sarcoma ; Kaposis sarcoma ; Lymph nodes ; Remission ; Sarcoma ; Stem cell transplantation ; Stem cells ; Transplantation ; Transplants & implants</subject><ispartof>Transplant infectious disease, 2021-06, Vol.23 (3), p.n/a</ispartof><rights>2020 Wiley Periodicals LLC</rights><rights>2021 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2975-13eb6f06faf4489089767d4bcf8ba3c45a3b4a9c8c03725cc34a55bc9602a3b53</citedby><cites>FETCH-LOGICAL-c2975-13eb6f06faf4489089767d4bcf8ba3c45a3b4a9c8c03725cc34a55bc9602a3b53</cites><orcidid>0000-0002-8507-1670</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Ftid.13525$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Ftid.13525$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,27905,27906,45555,45556</link.rule.ids></links><search><creatorcontrib>Valero‐Arrese, Lorena</creatorcontrib><creatorcontrib>Benítez‐Carabante, María Isabel</creatorcontrib><creatorcontrib>Soques Vallejo, Elena</creatorcontrib><creatorcontrib>Roca, Isabel</creatorcontrib><creatorcontrib>Navarro Jiménez, Alexandra</creatorcontrib><creatorcontrib>Díaz‐de‐Heredia, Cristina</creatorcontrib><title>Kaposi sarcoma in a child after hematopoietic stem cell transplantation: Should pre‐transplant HHV‐8 screening be considered in recipients from high prevalence areas?</title><title>Transplant infectious disease</title><description>Kaposi sarcoma (KS) is an angioproliferative disease associated with human herpesvirus 8 (HHV‐8). 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Considering that, we propose that screening of HHV‐8 by antibody testing could be considered in HSCT donors/recipients from these areas.</description><subject>Anemia</subject><subject>Antibodies</subject><subject>Aplastic anemia</subject><subject>children</subject><subject>Hematopoietic stem cells</subject><subject>HHV‐8</subject><subject>HSCT</subject><subject>Immunosuppression</subject><subject>Kaposi sarcoma</subject><subject>Kaposis sarcoma</subject><subject>Lymph nodes</subject><subject>Remission</subject><subject>Sarcoma</subject><subject>Stem cell transplantation</subject><subject>Stem cells</subject><subject>Transplantation</subject><subject>Transplants & implants</subject><issn>1398-2273</issn><issn>1399-3062</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp1kbtO3UAQhi2USOFW5A1GokphWO_F9qaJECQ5KEgpuLTWeD3Gi-xdZ3cPiC6PwHPwWHmS-HAiUWWaGc18_z_Fn2UfC3ZcLHWSbHdcCMXVTrZbCK1zwUr-7nWuc84r8SHbi_GesaLSUu9mLz9w9tFCxGD8hGAdIJjBjh1gnyjAQBMmP3tLyRqIiSYwNI6QAro4j-gSJuvdZ7ga_HpRzYH-_H5-u8JqdbssaogmEDnr7qAlMN5F21GgbvMxkLGzJZci9MFPMNi7YWP0gCM5Q4CBMH45yN73OEY6_Nf3s5tvX6_PVvnlz-8XZ6eXueG6UnkhqC17VvbYS1lrVuuqrDrZmr5uURipULQStakNExVXxgiJSrVGl4wvJyX2s6Ot7xz8rzXF1Nz7dXDLy4YrKaXgJZML9WlLmeBjDNQ3c7AThqemYM0mimaJonmNYmFPtuyjHenp_2BzfXG-VfwFICaP9Q</recordid><startdate>202106</startdate><enddate>202106</enddate><creator>Valero‐Arrese, Lorena</creator><creator>Benítez‐Carabante, María Isabel</creator><creator>Soques Vallejo, Elena</creator><creator>Roca, Isabel</creator><creator>Navarro Jiménez, Alexandra</creator><creator>Díaz‐de‐Heredia, Cristina</creator><general>Wiley Subscription Services, Inc</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7U9</scope><scope>8FD</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>P64</scope><orcidid>https://orcid.org/0000-0002-8507-1670</orcidid></search><sort><creationdate>202106</creationdate><title>Kaposi sarcoma in a child after hematopoietic stem cell transplantation: Should pre‐transplant HHV‐8 screening be considered in recipients from high prevalence areas?</title><author>Valero‐Arrese, Lorena ; Benítez‐Carabante, María Isabel ; Soques Vallejo, Elena ; Roca, Isabel ; Navarro Jiménez, Alexandra ; Díaz‐de‐Heredia, Cristina</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2975-13eb6f06faf4489089767d4bcf8ba3c45a3b4a9c8c03725cc34a55bc9602a3b53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Anemia</topic><topic>Antibodies</topic><topic>Aplastic anemia</topic><topic>children</topic><topic>Hematopoietic stem cells</topic><topic>HHV‐8</topic><topic>HSCT</topic><topic>Immunosuppression</topic><topic>Kaposi sarcoma</topic><topic>Kaposis sarcoma</topic><topic>Lymph nodes</topic><topic>Remission</topic><topic>Sarcoma</topic><topic>Stem cell transplantation</topic><topic>Stem cells</topic><topic>Transplantation</topic><topic>Transplants & implants</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Valero‐Arrese, Lorena</creatorcontrib><creatorcontrib>Benítez‐Carabante, María Isabel</creatorcontrib><creatorcontrib>Soques Vallejo, Elena</creatorcontrib><creatorcontrib>Roca, Isabel</creatorcontrib><creatorcontrib>Navarro Jiménez, Alexandra</creatorcontrib><creatorcontrib>Díaz‐de‐Heredia, Cristina</creatorcontrib><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Transplant infectious disease</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Valero‐Arrese, Lorena</au><au>Benítez‐Carabante, María Isabel</au><au>Soques Vallejo, Elena</au><au>Roca, Isabel</au><au>Navarro Jiménez, Alexandra</au><au>Díaz‐de‐Heredia, Cristina</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Kaposi sarcoma in a child after hematopoietic stem cell transplantation: Should pre‐transplant HHV‐8 screening be considered in recipients from high prevalence areas?</atitle><jtitle>Transplant infectious disease</jtitle><date>2021-06</date><risdate>2021</risdate><volume>23</volume><issue>3</issue><epage>n/a</epage><issn>1398-2273</issn><eissn>1399-3062</eissn><abstract>Kaposi sarcoma (KS) is an angioproliferative disease associated with human herpesvirus 8 (HHV‐8). 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| identifier | ISSN: 1398-2273 |
| ispartof | Transplant infectious disease, 2021-06, Vol.23 (3), p.n/a |
| issn | 1398-2273 1399-3062 |
| language | eng |
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| source | Wiley Online Library Journals Frontfile Complete |
| subjects | Anemia Antibodies Aplastic anemia children Hematopoietic stem cells HHV‐8 HSCT Immunosuppression Kaposi sarcoma Kaposis sarcoma Lymph nodes Remission Sarcoma Stem cell transplantation Stem cells Transplantation Transplants & implants |
| title | Kaposi sarcoma in a child after hematopoietic stem cell transplantation: Should pre‐transplant HHV‐8 screening be considered in recipients from high prevalence areas? |
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