Diallyl trisulphide, a H2S donor, compromises the stem cell phenotype and restores thyroid‐specific gene expression in anaplastic thyroid carcinoma cells by targeting AKT‐SOX2 axis

It is widely accepted that anaplastic thyroid carcinoma (ATC), a rare, extremely aggressive malignant, is enriched by cancer stem cells (CSCs), which are closely related to the pathogenesis of ATC. In the present study, we demonstrated that diallyl trisulphide (DATS), a well‐known hydrogen sulphide...

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Veröffentlicht in:Phytotherapy research 2021-06, Vol.35 (6), p.3428-3443
Hauptverfasser: Zhang, Li, Xu, Shichen, Cheng, Xian, Zheng, Jiangxia, Wang, Yunping, Wu, Jing, Wang, Xiaowen, Wu, Liying, Yu, Huixin, Bao, Jiandong
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Sprache:eng
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