An incoherent feedforward loop formed by SirA/BarA, HilE and HilD is involved in controlling the growth cost of virulence factor expression by Salmonella Typhimurium

An intricate regulatory network controls the expression of Salmonella virulence genes. The transcriptional regulator HilD plays a central role in this network by controlling the expression of tens of genes mainly required for intestinal colonization. Accordingly, the expression of HilD is highly reg...

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Veröffentlicht in:	PLoS pathogens 2021-05, Vol.17 (5), p.e1009630-e1009630, Article 1009630
Hauptverfasser:	Perez-Morales, Deyanira, Nava-Galeana, Jessica, Rosales-Reyes, Roberto, Teehan, Paige, Yakhnin, Helen, Melchy-Perez, Erika I., Rosenstein, Yvonne, De la Cruz, Miguel A., Babitzke, Paul, Bustamante, Victor H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria Binding sites Biology and Life Sciences Colonization Feedforward control Gene expression Genes Infections Intestine Kinases Laboratories Life Sciences & Biomedicine Medicine and Health Sciences Microbiology Parasitology Phosphorylation Proteins Research and Analysis Methods Salmonella Science & Technology Signal transduction Subpopulations Transcription Virology Virulence Virulence factors
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