Effects of 6weeks of treatment with dapagliflozin, a sodium‐glucose co‐transporter‐2 inhibitor, on myocardial function and metabolism in patients with type 2 diabetes: A randomized, placebo‐controlled, exploratory study

AimTo explore the early effects of dapagliflozin on myocardial function and metabolism in patients with type 2 diabetes without heart failure.Materials and MethodsPatients with type 2 diabetes on metformin treatment were randomized to double‐blind, 6‐week placebo or dapagliflozin 10 mg daily treatme...

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Veröffentlicht in:	Diabetes, obesity & metabolism obesity & metabolism, 2021-07, Vol.23 (7), p.1505-1517
Hauptverfasser:	Oldgren, Jonas, Laurila, Sanna, Åkerblom, Axel, Aino Latva‐Rasku, Rebelos, Eleni, Isackson, Henrik, Saarenhovi, Maria, Eriksson, Olof, Heurling, Kerstin, Johansson, Edvin, Wilderäng, Ulrica, Karlsson, Cecilia, Esterline, Russell, Ferrannini, Ele, Oscarsson, Jan, Nuutila, Pirjo
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic acid Antidiabetics Body mass index Body weight Congestive heart failure Diabetes Diabetes mellitus (non-insulin dependent) Efficiency Fatty acids Fatty liver Glucose transporter Metabolism Metformin Oxygen consumption Perfusion Placebos Positron emission tomography Statistical analysis Structure-function relationships Ventricle
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