C2-Selective silylation of pyridines by a rhodium-aluminum complex

We have developed a C2-selective mono-silylation of a variety of pyridines using a Rh-Al complex. Both the site- and mono-selectivity are controlled via the pyridine coordination to the Lewis-acidic Al center prior to the activation of the pyridine C(2)-H bond at the proximal Rh center. A reaction m...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2021-06, Vol.57 (48), p.5957-596
Hauptverfasser:	Hara, Naofumi, Uemura, Nao, Nakao, Yoshiaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Aluminum Crystallography Hydrogen bonds Pyridines Reaction mechanisms Rhodium Selectivity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!