Induced Cell Death as a Possible Pathway of Antimutagenic Action

The existing concepts of antimutagenesis are briefly reviewed. Published reports on antimutagenic and proapoptotic properties of some polyphenols and compounds of other chemical groups obtained in representative in vitro and in vivo experiments on eukaryotic test systems are discussed. The relations...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2021-05, Vol.171 (1), p.1-14
Hauptverfasser: Eremina, N. V., Zhanataev, A. K., Durnev, A. D.
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container_title Bulletin of experimental biology and medicine
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creator Eremina, N. V.
Zhanataev, A. K.
Durnev, A. D.
description The existing concepts of antimutagenesis are briefly reviewed. Published reports on antimutagenic and proapoptotic properties of some polyphenols and compounds of other chemical groups obtained in representative in vitro and in vivo experiments on eukaryotic test systems are discussed. The relationships between the antimutagenic and proapoptotic properties of the analyzed compounds (naringin, apigenin, resveratrol, curcumin, N-acetylcysteine, etc .) are considered in favor of the hypothesis on induced cell death as an antimutagenic tool.
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subjects Acetylcysteine
Analysis
Antimutagenic Agents - pharmacology
Apoptosis
Biochemistry
Biomedical and Life Sciences
Biomedicine
Cell Biology
Cell Death
Curcumin
Internal Medicine
Laboratory Medicine
Pathology
Polyphenols
Resveratrol
Reviews
title Induced Cell Death as a Possible Pathway of Antimutagenic Action
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