Clotrimazole-loaded N-(2-hydroxy)-propyl-3-trimethylammonium, O-palmitoyl chitosan nanoparticles for topical treatment of vulvovaginal candidiasis

Vulvovaginal candidiasis (VVC) represents a considerable health burden for women. Despite the availability of a significant array of antifungal drugs and topical products, the management of the infection is not always effective, and new approaches are needed. Here, we explored cationic N-(2-hydroxy)...

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Veröffentlicht in:Acta biomaterialia 2021-04, Vol.125, p.312-321
Hauptverfasser: Facchinatto, William Marcondes, Galante, Joana, Mesquita, Letícia, Silva, Daniella Souza, Martins dos Santos, Danilo, Moraes, Tiago Bueno, Campana-Filho, Sérgio Paulo, Colnago, Luiz Alberto, Sarmento, Bruno, das Neves, José
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Sprache:eng
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