Resilience and its associated factors in brain tumor patients in Karachi, Pakistan: An analytical cross‐sectional study

Objectives This study assessed resilience in brain tumor patients at a tertiary care hospital in Pakistan (a lower middle‐income country; LMIC) and explored its relationship with patients' sociodemographic factors, clinical characteristics, social support, and mental health. Methods A cross‐sec...

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Veröffentlicht in:Psycho-oncology (Chichester, England) England), 2021-06, Vol.30 (6), p.882-891
Hauptverfasser: Zahid, Nida, Martins, Russell Seth, Zahid, Wajeeha, Khalid, Wardah, Azam, Iqbal, Bhamani, Shireen Shehzad, Ahmad, Khabir, Jabbar, AdnanAbdul, Shamim, Muhammad Shahzad, Khan, Rashid Jooma, Javed, Gohar, Bari, Ehsan, Asad, Nargis, Enam, Syed Ather
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container_issue 6
container_start_page 882
container_title Psycho-oncology (Chichester, England)
container_volume 30
creator Zahid, Nida
Martins, Russell Seth
Zahid, Wajeeha
Khalid, Wardah
Azam, Iqbal
Bhamani, Shireen Shehzad
Ahmad, Khabir
Jabbar, AdnanAbdul
Shamim, Muhammad Shahzad
Khan, Rashid Jooma
Javed, Gohar
Bari, Ehsan
Asad, Nargis
Enam, Syed Ather
description Objectives This study assessed resilience in brain tumor patients at a tertiary care hospital in Pakistan (a lower middle‐income country; LMIC) and explored its relationship with patients' sociodemographic factors, clinical characteristics, social support, and mental health. Methods A cross‐sectional survey was conducted amongst adult (≥18 years) patients with brain tumor at the Aga Khan University Hospital, Pakistan. Resilience was assessed by Wagnild and Young's Resilience Scale, and patients' psychosocial characteristics by the Hospital Anxiety and Depression Scale and the Enriched Social Support Instrument. Results A total of 250 patients were included (mean age: 44 years; 68% males), with majority (97.6%) having high social support and only 4.4% and 2% having symptomatic depression and anxiety, respectively. On multivariable linear regression adjusted for covariates, lower resilience was associated with not being involved in household decision‐making (Adjusted Beta Coefficient: 4.58 [95% Confidence Interval:−7.59, −1.56]), not currently working (−2.80 [−4.61, −0.99]), undergoing multiple neurosurgical interventions such as tumor biopsies or resections (−8.64 [−13.11, −4.16]), receiving chemotherapy (−5.17 [−9.51, −0.83]) or combination adjuvant therapy (−2.91 [−5.14, −0.67]), low social support (−7.77 [−13.73, 1.81]), mild depression (−13.00 [‐17.00,‐8.99]) or symptomatic depression (−19.79 [−24.69, −14.89]), and mild anxiety (−4.24 [−7.98, −0.50]). Conclusion Our study highlights the function of familial/household role and working status in mediating resilience, and demonstrates the well‐known protective effect of resilience for mental health in brain tumor patients in Pakistan, a South‐Asian LMIC. These findings are of clinical relevance with regards to the development of culture‐specific evidence‐based resilience‐building interventions that may help patients with brain tumors to cope with the psychological distress of cancer.
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Methods A cross‐sectional survey was conducted amongst adult (≥18 years) patients with brain tumor at the Aga Khan University Hospital, Pakistan. Resilience was assessed by Wagnild and Young's Resilience Scale, and patients' psychosocial characteristics by the Hospital Anxiety and Depression Scale and the Enriched Social Support Instrument. Results A total of 250 patients were included (mean age: 44 years; 68% males), with majority (97.6%) having high social support and only 4.4% and 2% having symptomatic depression and anxiety, respectively. On multivariable linear regression adjusted for covariates, lower resilience was associated with not being involved in household decision‐making (Adjusted Beta Coefficient: 4.58 [95% Confidence Interval:−7.59, −1.56]), not currently working (−2.80 [−4.61, −0.99]), undergoing multiple neurosurgical interventions such as tumor biopsies or resections (−8.64 [−13.11, −4.16]), receiving chemotherapy (−5.17 [−9.51, −0.83]) or combination adjuvant therapy (−2.91 [−5.14, −0.67]), low social support (−7.77 [−13.73, 1.81]), mild depression (−13.00 [‐17.00,‐8.99]) or symptomatic depression (−19.79 [−24.69, −14.89]), and mild anxiety (−4.24 [−7.98, −0.50]). Conclusion Our study highlights the function of familial/household role and working status in mediating resilience, and demonstrates the well‐known protective effect of resilience for mental health in brain tumor patients in Pakistan, a South‐Asian LMIC. These findings are of clinical relevance with regards to the development of culture‐specific evidence‐based resilience‐building interventions that may help patients with brain tumors to cope with the psychological distress of cancer.</description><identifier>ISSN: 1057-9249</identifier><identifier>EISSN: 1099-1611</identifier><identifier>DOI: 10.1002/pon.5661</identifier><identifier>PMID: 33609048</identifier><language>eng</language><publisher>HOBOKEN: Wiley</publisher><subject>Adjuvant therapy ; Anxiety ; Biomedical Social Sciences ; Biopsy ; Brain cancer ; brain tumor ; Brain tumors ; Cancer ; Chemotherapy ; Combination therapy ; Cross-sectional studies ; depression ; developing countries ; Intervention ; Life Sciences &amp; Biomedicine ; Males ; Men ; Mental depression ; Mental disorders ; Mental health ; Oncology ; Psychological distress ; Psychology ; Psychology, Multidisciplinary ; Psychosocial factors ; psycho‐oncology ; Resilience ; Science &amp; Technology ; Social Sciences ; Social Sciences, Biomedical ; Social support ; Sociodemographics ; Tumors</subject><ispartof>Psycho-oncology (Chichester, England), 2021-06, Vol.30 (6), p.882-891</ispartof><rights>2021 John Wiley &amp; Sons Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>true</woscitedreferencessubscribed><woscitedreferencescount>9</woscitedreferencescount><woscitedreferencesoriginalsourcerecordid>wos000627030400001</woscitedreferencesoriginalsourcerecordid><citedby>FETCH-LOGICAL-c4151-eb17ae5e9b4d4edc3efd2e7b72a55623bbbd94eefed7bffd82d3c160d6768fcd3</citedby><cites>FETCH-LOGICAL-c4151-eb17ae5e9b4d4edc3efd2e7b72a55623bbbd94eefed7bffd82d3c160d6768fcd3</cites><orcidid>0000-0001-8812-9463 ; 0000-0002-7776-0281</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fpon.5661$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fpon.5661$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,782,786,1419,27931,27932,31006,39264,39265,45581,45582</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33609048$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zahid, Nida</creatorcontrib><creatorcontrib>Martins, Russell Seth</creatorcontrib><creatorcontrib>Zahid, Wajeeha</creatorcontrib><creatorcontrib>Khalid, Wardah</creatorcontrib><creatorcontrib>Azam, Iqbal</creatorcontrib><creatorcontrib>Bhamani, Shireen Shehzad</creatorcontrib><creatorcontrib>Ahmad, Khabir</creatorcontrib><creatorcontrib>Jabbar, AdnanAbdul</creatorcontrib><creatorcontrib>Shamim, Muhammad Shahzad</creatorcontrib><creatorcontrib>Khan, Rashid Jooma</creatorcontrib><creatorcontrib>Javed, Gohar</creatorcontrib><creatorcontrib>Bari, Ehsan</creatorcontrib><creatorcontrib>Asad, Nargis</creatorcontrib><creatorcontrib>Enam, Syed Ather</creatorcontrib><title>Resilience and its associated factors in brain tumor patients in Karachi, Pakistan: An analytical cross‐sectional study</title><title>Psycho-oncology (Chichester, England)</title><addtitle>PSYCHO-ONCOLOGY</addtitle><addtitle>Psychooncology</addtitle><description>Objectives This study assessed resilience in brain tumor patients at a tertiary care hospital in Pakistan (a lower middle‐income country; LMIC) and explored its relationship with patients' sociodemographic factors, clinical characteristics, social support, and mental health. Methods A cross‐sectional survey was conducted amongst adult (≥18 years) patients with brain tumor at the Aga Khan University Hospital, Pakistan. Resilience was assessed by Wagnild and Young's Resilience Scale, and patients' psychosocial characteristics by the Hospital Anxiety and Depression Scale and the Enriched Social Support Instrument. Results A total of 250 patients were included (mean age: 44 years; 68% males), with majority (97.6%) having high social support and only 4.4% and 2% having symptomatic depression and anxiety, respectively. On multivariable linear regression adjusted for covariates, lower resilience was associated with not being involved in household decision‐making (Adjusted Beta Coefficient: 4.58 [95% Confidence Interval:−7.59, −1.56]), not currently working (−2.80 [−4.61, −0.99]), undergoing multiple neurosurgical interventions such as tumor biopsies or resections (−8.64 [−13.11, −4.16]), receiving chemotherapy (−5.17 [−9.51, −0.83]) or combination adjuvant therapy (−2.91 [−5.14, −0.67]), low social support (−7.77 [−13.73, 1.81]), mild depression (−13.00 [‐17.00,‐8.99]) or symptomatic depression (−19.79 [−24.69, −14.89]), and mild anxiety (−4.24 [−7.98, −0.50]). Conclusion Our study highlights the function of familial/household role and working status in mediating resilience, and demonstrates the well‐known protective effect of resilience for mental health in brain tumor patients in Pakistan, a South‐Asian LMIC. These findings are of clinical relevance with regards to the development of culture‐specific evidence‐based resilience‐building interventions that may help patients with brain tumors to cope with the psychological distress of cancer.</description><subject>Adjuvant therapy</subject><subject>Anxiety</subject><subject>Biomedical Social Sciences</subject><subject>Biopsy</subject><subject>Brain cancer</subject><subject>brain tumor</subject><subject>Brain tumors</subject><subject>Cancer</subject><subject>Chemotherapy</subject><subject>Combination therapy</subject><subject>Cross-sectional studies</subject><subject>depression</subject><subject>developing countries</subject><subject>Intervention</subject><subject>Life Sciences &amp; Biomedicine</subject><subject>Males</subject><subject>Men</subject><subject>Mental depression</subject><subject>Mental disorders</subject><subject>Mental health</subject><subject>Oncology</subject><subject>Psychological distress</subject><subject>Psychology</subject><subject>Psychology, Multidisciplinary</subject><subject>Psychosocial factors</subject><subject>psycho‐oncology</subject><subject>Resilience</subject><subject>Science &amp; 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Martins, Russell Seth ; Zahid, Wajeeha ; Khalid, Wardah ; Azam, Iqbal ; Bhamani, Shireen Shehzad ; Ahmad, Khabir ; Jabbar, AdnanAbdul ; Shamim, Muhammad Shahzad ; Khan, Rashid Jooma ; Javed, Gohar ; Bari, Ehsan ; Asad, Nargis ; Enam, Syed Ather</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4151-eb17ae5e9b4d4edc3efd2e7b72a55623bbbd94eefed7bffd82d3c160d6768fcd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Adjuvant therapy</topic><topic>Anxiety</topic><topic>Biomedical Social Sciences</topic><topic>Biopsy</topic><topic>Brain cancer</topic><topic>brain tumor</topic><topic>Brain tumors</topic><topic>Cancer</topic><topic>Chemotherapy</topic><topic>Combination therapy</topic><topic>Cross-sectional studies</topic><topic>depression</topic><topic>developing countries</topic><topic>Intervention</topic><topic>Life Sciences &amp; Biomedicine</topic><topic>Males</topic><topic>Men</topic><topic>Mental depression</topic><topic>Mental disorders</topic><topic>Mental health</topic><topic>Oncology</topic><topic>Psychological distress</topic><topic>Psychology</topic><topic>Psychology, Multidisciplinary</topic><topic>Psychosocial factors</topic><topic>psycho‐oncology</topic><topic>Resilience</topic><topic>Science &amp; 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LMIC) and explored its relationship with patients' sociodemographic factors, clinical characteristics, social support, and mental health. Methods A cross‐sectional survey was conducted amongst adult (≥18 years) patients with brain tumor at the Aga Khan University Hospital, Pakistan. Resilience was assessed by Wagnild and Young's Resilience Scale, and patients' psychosocial characteristics by the Hospital Anxiety and Depression Scale and the Enriched Social Support Instrument. Results A total of 250 patients were included (mean age: 44 years; 68% males), with majority (97.6%) having high social support and only 4.4% and 2% having symptomatic depression and anxiety, respectively. On multivariable linear regression adjusted for covariates, lower resilience was associated with not being involved in household decision‐making (Adjusted Beta Coefficient: 4.58 [95% Confidence Interval:−7.59, −1.56]), not currently working (−2.80 [−4.61, −0.99]), undergoing multiple neurosurgical interventions such as tumor biopsies or resections (−8.64 [−13.11, −4.16]), receiving chemotherapy (−5.17 [−9.51, −0.83]) or combination adjuvant therapy (−2.91 [−5.14, −0.67]), low social support (−7.77 [−13.73, 1.81]), mild depression (−13.00 [‐17.00,‐8.99]) or symptomatic depression (−19.79 [−24.69, −14.89]), and mild anxiety (−4.24 [−7.98, −0.50]). Conclusion Our study highlights the function of familial/household role and working status in mediating resilience, and demonstrates the well‐known protective effect of resilience for mental health in brain tumor patients in Pakistan, a South‐Asian LMIC. These findings are of clinical relevance with regards to the development of culture‐specific evidence‐based resilience‐building interventions that may help patients with brain tumors to cope with the psychological distress of cancer.</abstract><cop>HOBOKEN</cop><pub>Wiley</pub><pmid>33609048</pmid><doi>10.1002/pon.5661</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0001-8812-9463</orcidid><orcidid>https://orcid.org/0000-0002-7776-0281</orcidid></addata></record>
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subjects Adjuvant therapy
Anxiety
Biomedical Social Sciences
Biopsy
Brain cancer
brain tumor
Brain tumors
Cancer
Chemotherapy
Combination therapy
Cross-sectional studies
depression
developing countries
Intervention
Life Sciences & Biomedicine
Males
Men
Mental depression
Mental disorders
Mental health
Oncology
Psychological distress
Psychology
Psychology, Multidisciplinary
Psychosocial factors
psycho‐oncology
Resilience
Science & Technology
Social Sciences
Social Sciences, Biomedical
Social support
Sociodemographics
Tumors
title Resilience and its associated factors in brain tumor patients in Karachi, Pakistan: An analytical cross‐sectional study
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