e -MagnetoMethyl IP: a magnetic nanoparticle-mediated immunoprecipitation and electrochemical detection method for global DNA methylation

The quantification of global 5-methylcytosine (5mC) content has emerged as a promising approach for the diagnosis and prognosis of cancers. However, conventional methods for the global 5mC analysis require large quantities of DNA and may not be useful for liquid biopsy applications, where the amount...

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Veröffentlicht in:	Analyst (London) 2021-06, Vol.146 (11), p.3654-3665
Hauptverfasser:	Farhana, Fatema Zerin, Umer, Muhammad, Saeed, Ayad, Pannu, Amandeep Singh, Husaini, Sediqa, Sonar, Prashant, Firoz, Shakhawat H, Shiddiky, Muhammad J A
Format:	Artikel
Sprache:	eng
Schlagworte:	Ammonia Antibodies Biopsy DNA methylation Electrochemical analysis Gold Iron oxides Nanoparticles Signal generation
Online-Zugang:	Volltext
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