An Unusual Case of Muscle Twitching: Its LGI1

An Unusual Case of Muscle Twitching: Its LGI1

A 50-year-old male, presented with a two-months history of ascending paresthesias, with continuous twitchings over the body, associated with insomnia. His electromyography (EMG) revealed neuromyotonia and was diagnosed as a case of peripheral nerve hyperexcitability (PNH) syndrome due to Leucin-rich...

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Veröffentlicht in:Neurology India 2021-03, Vol.69 (2), p.493-494
Hauptverfasser: Tomar, Laxmikant, Shah, Dhrumil, Ranjan, Rajeev, Rohatgi, Anshu, Agrawal, C
Format: Artikel
Sprache:eng
Schlagworte:
Case studies
Glioma
Health aspects
Membrane proteins
Neurologic manifestations of general diseases
Peripheral nerve diseases
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Zusammenfassung:A 50-year-old male, presented with a two-months history of ascending paresthesias, with continuous twitchings over the body, associated with insomnia. His electromyography (EMG) revealed neuromyotonia and was diagnosed as a case of peripheral nerve hyperexcitability (PNH) syndrome due to Leucin-rich glioma-inactivated 1 (LGI1) antibody. He showed significant improvement with intravenous immunoglobulin and carbamazepine.
ISSN:0028-3886
1998-4022
DOI:10.4103/0028-3886.314549