Clinicogenetical Variants of Progressive External Ophthalmoplegia - An Especial Review of Non-ophthalmic Manifestations
Progressive external ophthalmoplegia (PEO) is a slowly progressive myopathy characterized by extraocular muscles involvement, leading to frozen eyes without diplopia. The pattern of inheritance may be mitochondrial, autosomal dominant or, rarely, autosomal recessive. Sporadic forms were also reporte...
Gespeichert in:
| Veröffentlicht in: | Neurology India 2020-07, Vol.68 (4), p.760-768 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 768 |
|---|---|
| container_issue | 4 |
| container_start_page | 760 |
| container_title | Neurology India |
| container_volume | 68 |
| creator | Maghbooli, Mehdi Ghaffarpour, Majid Ghazizadeh, Taher Shalbaf, Nazanin MalekMahmoudi, Ghazal |
| description | Progressive external ophthalmoplegia (PEO) is a slowly progressive myopathy characterized by extraocular muscles involvement, leading to frozen eyes without diplopia. The pattern of inheritance may be mitochondrial, autosomal dominant or, rarely, autosomal recessive. Sporadic forms were also reported. Muscular involvement other than extraocular muscles may occur with varying degrees of weakness, but this mostly happens many years after the disease begins. There are also scattered data about systemic signs besides ophthalmoplegia. This article aims to review non-ophthalmic findings of PEO from a clinicogenetical point of view. |
| doi_str_mv | 10.4103/0028-3886.293454 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_journals_2532913865</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A634197224</galeid><sourcerecordid>A634197224</sourcerecordid><originalsourceid>FETCH-LOGICAL-c491g-e47ae682a67d9a8eec8151f127ed1e81135474e70661dcfb3c0722f936dc9bb23</originalsourceid><addsrcrecordid>eNptkt1v0zAUxS0EYmXwzhOKxHOKv5LYj6XqAGkwhIBXy3VuMm-uHex0gf8eR-0Gkyo_WPb9nWPde4zQa4KXnGD2DmMqSiZEvaSS8Yo_QQsipSg5pvQpWjyUz9CLlG7ykTFCn6MzRkUlBSELNK2d9daEHjyM1mhX_NTRaj-mInTF1xj6CCnZOyg2v0eIPgNXw_V4rd0uDA56q4uyWPlikwYwNle_wZ2FaRZ_Cb4MR9aa4rP2toM06tEGn16iZ512CV4d93P042Lzff2xvLz68Gm9uiwNl6QvgTcaakF13bRSCwAjSEU6QhtoCeQOWMUbDg2ua9KabssMbijtJKtbI7dbys7R24PvEMOvfX5e3YT93EZStGJUEibq6h_VawfK-i6MUZudTUatasaJzKY8U-UJap5c1C546Gy-fsQvT_B5tZAHclKADwITQ0oROjVEu9PxjyJYzYGrOVE1J6oOgWfJm2N_--0O2gfBfcIZeH8ApuBygOnW7SeIKrO3PkyPjMv_jFVTY3X_N9hftzW6Ag</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2532913865</pqid></control><display><type>article</type><title>Clinicogenetical Variants of Progressive External Ophthalmoplegia - An Especial Review of Non-ophthalmic Manifestations</title><source>MEDLINE</source><source>EZB Electronic Journals Library</source><creator>Maghbooli, Mehdi ; Ghaffarpour, Majid ; Ghazizadeh, Taher ; Shalbaf, Nazanin ; MalekMahmoudi, Ghazal</creator><creatorcontrib>Maghbooli, Mehdi ; Ghaffarpour, Majid ; Ghazizadeh, Taher ; Shalbaf, Nazanin ; MalekMahmoudi, Ghazal</creatorcontrib><description>Progressive external ophthalmoplegia (PEO) is a slowly progressive myopathy characterized by extraocular muscles involvement, leading to frozen eyes without diplopia. The pattern of inheritance may be mitochondrial, autosomal dominant or, rarely, autosomal recessive. Sporadic forms were also reported. Muscular involvement other than extraocular muscles may occur with varying degrees of weakness, but this mostly happens many years after the disease begins. There are also scattered data about systemic signs besides ophthalmoplegia. This article aims to review non-ophthalmic findings of PEO from a clinicogenetical point of view.</description><identifier>ISSN: 0028-3886</identifier><identifier>EISSN: 1998-4022</identifier><identifier>DOI: 10.4103/0028-3886.293454</identifier><identifier>PMID: 32859811</identifier><language>eng</language><publisher>India: Wolters Kluwer India Pvt. Ltd</publisher><subject>Brain diseases ; Development and progression ; Diplopia ; DNA, Mitochondrial ; Humans ; Oculomotor Muscles ; Ophthalmoplegia ; Ophthalmoplegia - genetics ; Ophthalmoplegia, Chronic Progressive External - genetics</subject><ispartof>Neurology India, 2020-07, Vol.68 (4), p.760-768</ispartof><rights>COPYRIGHT 2020 Medknow Publications and Media Pvt. Ltd.</rights><rights>2020. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c491g-e47ae682a67d9a8eec8151f127ed1e81135474e70661dcfb3c0722f936dc9bb23</citedby><cites>FETCH-LOGICAL-c491g-e47ae682a67d9a8eec8151f127ed1e81135474e70661dcfb3c0722f936dc9bb23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32859811$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Maghbooli, Mehdi</creatorcontrib><creatorcontrib>Ghaffarpour, Majid</creatorcontrib><creatorcontrib>Ghazizadeh, Taher</creatorcontrib><creatorcontrib>Shalbaf, Nazanin</creatorcontrib><creatorcontrib>MalekMahmoudi, Ghazal</creatorcontrib><title>Clinicogenetical Variants of Progressive External Ophthalmoplegia - An Especial Review of Non-ophthalmic Manifestations</title><title>Neurology India</title><addtitle>Neurol India</addtitle><description>Progressive external ophthalmoplegia (PEO) is a slowly progressive myopathy characterized by extraocular muscles involvement, leading to frozen eyes without diplopia. The pattern of inheritance may be mitochondrial, autosomal dominant or, rarely, autosomal recessive. Sporadic forms were also reported. Muscular involvement other than extraocular muscles may occur with varying degrees of weakness, but this mostly happens many years after the disease begins. There are also scattered data about systemic signs besides ophthalmoplegia. This article aims to review non-ophthalmic findings of PEO from a clinicogenetical point of view.</description><subject>Brain diseases</subject><subject>Development and progression</subject><subject>Diplopia</subject><subject>DNA, Mitochondrial</subject><subject>Humans</subject><subject>Oculomotor Muscles</subject><subject>Ophthalmoplegia</subject><subject>Ophthalmoplegia - genetics</subject><subject>Ophthalmoplegia, Chronic Progressive External - genetics</subject><issn>0028-3886</issn><issn>1998-4022</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNptkt1v0zAUxS0EYmXwzhOKxHOKv5LYj6XqAGkwhIBXy3VuMm-uHex0gf8eR-0Gkyo_WPb9nWPde4zQa4KXnGD2DmMqSiZEvaSS8Yo_QQsipSg5pvQpWjyUz9CLlG7ykTFCn6MzRkUlBSELNK2d9daEHjyM1mhX_NTRaj-mInTF1xj6CCnZOyg2v0eIPgNXw_V4rd0uDA56q4uyWPlikwYwNle_wZ2FaRZ_Cb4MR9aa4rP2toM06tEGn16iZ512CV4d93P042Lzff2xvLz68Gm9uiwNl6QvgTcaakF13bRSCwAjSEU6QhtoCeQOWMUbDg2ua9KabssMbijtJKtbI7dbys7R24PvEMOvfX5e3YT93EZStGJUEibq6h_VawfK-i6MUZudTUatasaJzKY8U-UJap5c1C546Gy-fsQvT_B5tZAHclKADwITQ0oROjVEu9PxjyJYzYGrOVE1J6oOgWfJm2N_--0O2gfBfcIZeH8ApuBygOnW7SeIKrO3PkyPjMv_jFVTY3X_N9hftzW6Ag</recordid><startdate>20200701</startdate><enddate>20200701</enddate><creator>Maghbooli, Mehdi</creator><creator>Ghaffarpour, Majid</creator><creator>Ghazizadeh, Taher</creator><creator>Shalbaf, Nazanin</creator><creator>MalekMahmoudi, Ghazal</creator><general>Wolters Kluwer India Pvt. Ltd</general><general>Medknow Publications and Media Pvt. Ltd</general><general>Medknow Publications & Media Pvt. Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope></search><sort><creationdate>20200701</creationdate><title>Clinicogenetical Variants of Progressive External Ophthalmoplegia - An Especial Review of Non-ophthalmic Manifestations</title><author>Maghbooli, Mehdi ; Ghaffarpour, Majid ; Ghazizadeh, Taher ; Shalbaf, Nazanin ; MalekMahmoudi, Ghazal</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c491g-e47ae682a67d9a8eec8151f127ed1e81135474e70661dcfb3c0722f936dc9bb23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Brain diseases</topic><topic>Development and progression</topic><topic>Diplopia</topic><topic>DNA, Mitochondrial</topic><topic>Humans</topic><topic>Oculomotor Muscles</topic><topic>Ophthalmoplegia</topic><topic>Ophthalmoplegia - genetics</topic><topic>Ophthalmoplegia, Chronic Progressive External - genetics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Maghbooli, Mehdi</creatorcontrib><creatorcontrib>Ghaffarpour, Majid</creatorcontrib><creatorcontrib>Ghazizadeh, Taher</creatorcontrib><creatorcontrib>Shalbaf, Nazanin</creatorcontrib><creatorcontrib>MalekMahmoudi, Ghazal</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest research library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><jtitle>Neurology India</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Maghbooli, Mehdi</au><au>Ghaffarpour, Majid</au><au>Ghazizadeh, Taher</au><au>Shalbaf, Nazanin</au><au>MalekMahmoudi, Ghazal</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinicogenetical Variants of Progressive External Ophthalmoplegia - An Especial Review of Non-ophthalmic Manifestations</atitle><jtitle>Neurology India</jtitle><addtitle>Neurol India</addtitle><date>2020-07-01</date><risdate>2020</risdate><volume>68</volume><issue>4</issue><spage>760</spage><epage>768</epage><pages>760-768</pages><issn>0028-3886</issn><eissn>1998-4022</eissn><abstract>Progressive external ophthalmoplegia (PEO) is a slowly progressive myopathy characterized by extraocular muscles involvement, leading to frozen eyes without diplopia. The pattern of inheritance may be mitochondrial, autosomal dominant or, rarely, autosomal recessive. Sporadic forms were also reported. Muscular involvement other than extraocular muscles may occur with varying degrees of weakness, but this mostly happens many years after the disease begins. There are also scattered data about systemic signs besides ophthalmoplegia. This article aims to review non-ophthalmic findings of PEO from a clinicogenetical point of view.</abstract><cop>India</cop><pub>Wolters Kluwer India Pvt. Ltd</pub><pmid>32859811</pmid><doi>10.4103/0028-3886.293454</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0028-3886 |
| ispartof | Neurology India, 2020-07, Vol.68 (4), p.760-768 |
| issn | 0028-3886 1998-4022 |
| language | eng |
| recordid | cdi_proquest_journals_2532913865 |
| source | MEDLINE; EZB Electronic Journals Library |
| subjects | Brain diseases Development and progression Diplopia DNA, Mitochondrial Humans Oculomotor Muscles Ophthalmoplegia Ophthalmoplegia - genetics Ophthalmoplegia, Chronic Progressive External - genetics |
| title | Clinicogenetical Variants of Progressive External Ophthalmoplegia - An Especial Review of Non-ophthalmic Manifestations |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-22T15%3A14%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Clinicogenetical%20Variants%20of%20Progressive%20External%20Ophthalmoplegia%20-%20An%20Especial%20Review%20of%20Non-ophthalmic%20Manifestations&rft.jtitle=Neurology%20India&rft.au=Maghbooli,%20Mehdi&rft.date=2020-07-01&rft.volume=68&rft.issue=4&rft.spage=760&rft.epage=768&rft.pages=760-768&rft.issn=0028-3886&rft.eissn=1998-4022&rft_id=info:doi/10.4103/0028-3886.293454&rft_dat=%3Cgale_proqu%3EA634197224%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2532913865&rft_id=info:pmid/32859811&rft_galeid=A634197224&rfr_iscdi=true |