Herbal supplement usage among cancer patients: A questionnaire-based survey
Background: Herbal supplements (HS) are one of the most commonly used complementary and alternative medicines in cancer. Reduced therapeutic efficacy of prescription anticancer agents through unwarranted herb-drug interactions is a major efficacy/safety concern. In view of the rising cancer prevalen...
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| Veröffentlicht in: | Journal of cancer research and therapeutics 2021-01, Vol.17 (1), p.136-141 |
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| creator | Kanimozhi, Thirunavukkarasu Hindu, Kalluru Maheshvari, Yuvaraj Khushnidha, Y Kumaravel, Mahendrian Srinivas, K Manickavasagam, M Mangathayaru, Kalachaveedu |
| description | Background: Herbal supplements (HS) are one of the most commonly used complementary and alternative medicines in cancer. Reduced therapeutic efficacy of prescription anticancer agents through unwarranted herb-drug interactions is a major efficacy/safety concern. In view of the rising cancer prevalence in India along with a high degree of reliance and cultural acceptability in favor of traditional medicine drugs, prevalence data exclusively of HS usage during cancer treatment are of considerable epidemiological significance.
Methodology: This questionnaire-based prospective observational study aimed at estimating the prevalence of HS among cancer patients during treatment at our tertiary care medical center. Taken on a population of 220 patients within a period of 9 months, data were generated by a customized validated questionnaire and the same processed by IBM SPSS Statistics for Windows, version XXIV, Armonk, NY: IBM Corp. Differences between HS use and nonuse with respect to demographic, disease, and treatment characteristics were assessed by Chi-square test. For examining the latter variables as possible predictors of HS usage, they were entered into bivariate logistic regression with odds ratio and confidence intervals calculated for each.
Results: Out of 220 patients, 57 (26%) were HS users and 163 (74%) were nonusers. Majority of the users (42.1%) were on self-prepared folklore herbal medicine postdiagnosis of cancer (57.9%), the most common reason cited being symptom palliation (35.1%) on the advice of friends and family (64.9%). Fear of disapproval was the most common reason cited (68.4%) for not disclosing HS usage to the physician.
Conclusion: Chemotherapy and unemployment are predictors of HS usage, and there is a significant association between occupation status and HS usage. This first study on HS prevalence among South Indian population proposes the need for a more robust evidence base for understanding all aspects of HS use in cancer. |
| doi_str_mv | 10.4103/jcrt.JCRT_612_18 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_journals_2532657901</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A655948370</galeid><sourcerecordid>A655948370</sourcerecordid><originalsourceid>FETCH-LOGICAL-c498e-553d7374ee470e6942a43bbdfb762a4b6df3e0dea5413bd64098457c86fb96873</originalsourceid><addsrcrecordid>eNp1kUtv1DAURi0EokNhzwpFYp3Bjt_sRiOghUpIqKwt27kZZZrYwU466r_HZVoe0iAvbNnnu9dXB6HXBK8ZwfTd3qd5_Xn77doI0hiinqAV0VrVjFD1FK2wlrQmTDVn6EXOe4y5bBr1HJ1RKhtKGFuhLxeQnB2qvEzTACOEuVqy3UFlxxh2lbfBQ6omO_flKb-vNtWPBfLcxxBsn6B2NkNb0ukW7l6iZ50dMrx62M_R948frrcX9dXXT5fbzVXtmVZQc05bSSUDYBKD0KyxjDrXdk6KcnSi7SjgFiwvY7hWMKwV49Ir0TktlKTn6O2x7pTir9-YfVxSKC1Nw2kjuNSY_KF2dgDThy7Oyfqxz95sBOeaKSpxoeoT1A4CJDvEAF1frv_h1yf4sloYe38ygI8Bn2LOCTozpX606c4QbO4lmnuJ5i-JJfLmYb7FjdD-DjxaK8DlETjEYYaUb4blAMkU9ibEw38LG0KFOfo2j77pT9eCsUE</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2532657901</pqid></control><display><type>article</type><title>Herbal supplement usage among cancer patients: A questionnaire-based survey</title><source>MEDLINE</source><source>Medknow Open Access Medical Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Kanimozhi, Thirunavukkarasu ; Hindu, Kalluru ; Maheshvari, Yuvaraj ; Khushnidha, Y ; Kumaravel, Mahendrian ; Srinivas, K ; Manickavasagam, M ; Mangathayaru, Kalachaveedu</creator><creatorcontrib>Kanimozhi, Thirunavukkarasu ; Hindu, Kalluru ; Maheshvari, Yuvaraj ; Khushnidha, Y ; Kumaravel, Mahendrian ; Srinivas, K ; Manickavasagam, M ; Mangathayaru, Kalachaveedu</creatorcontrib><description>Background: Herbal supplements (HS) are one of the most commonly used complementary and alternative medicines in cancer. Reduced therapeutic efficacy of prescription anticancer agents through unwarranted herb-drug interactions is a major efficacy/safety concern. In view of the rising cancer prevalence in India along with a high degree of reliance and cultural acceptability in favor of traditional medicine drugs, prevalence data exclusively of HS usage during cancer treatment are of considerable epidemiological significance.
Methodology: This questionnaire-based prospective observational study aimed at estimating the prevalence of HS among cancer patients during treatment at our tertiary care medical center. Taken on a population of 220 patients within a period of 9 months, data were generated by a customized validated questionnaire and the same processed by IBM SPSS Statistics for Windows, version XXIV, Armonk, NY: IBM Corp. Differences between HS use and nonuse with respect to demographic, disease, and treatment characteristics were assessed by Chi-square test. For examining the latter variables as possible predictors of HS usage, they were entered into bivariate logistic regression with odds ratio and confidence intervals calculated for each.
Results: Out of 220 patients, 57 (26%) were HS users and 163 (74%) were nonusers. Majority of the users (42.1%) were on self-prepared folklore herbal medicine postdiagnosis of cancer (57.9%), the most common reason cited being symptom palliation (35.1%) on the advice of friends and family (64.9%). Fear of disapproval was the most common reason cited (68.4%) for not disclosing HS usage to the physician.
Conclusion: Chemotherapy and unemployment are predictors of HS usage, and there is a significant association between occupation status and HS usage. This first study on HS prevalence among South Indian population proposes the need for a more robust evidence base for understanding all aspects of HS use in cancer.</description><identifier>ISSN: 0973-1482</identifier><identifier>EISSN: 1998-4138</identifier><identifier>DOI: 10.4103/jcrt.JCRT_612_18</identifier><identifier>PMID: 33723144</identifier><language>eng</language><publisher>India: Wolters Kluwer India Pvt. Ltd</publisher><subject>Adult ; Cancer ; Cancer patients ; Care and treatment ; Dietary supplements ; Dietary Supplements - statistics & numerical data ; Employment - statistics & numerical data ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; India ; Male ; Medicine, Botanic ; Medicine, Herbal ; Middle Aged ; Neoplasms - drug therapy ; Phytotherapy - methods ; Prospective Studies ; Questionnaires ; Surveys ; Surveys and Questionnaires - statistics & numerical data ; Young Adult</subject><ispartof>Journal of cancer research and therapeutics, 2021-01, Vol.17 (1), p.136-141</ispartof><rights>COPYRIGHT 2021 Medknow Publications and Media Pvt. Ltd.</rights><rights>2021. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c498e-553d7374ee470e6942a43bbdfb762a4b6df3e0dea5413bd64098457c86fb96873</citedby><cites>FETCH-LOGICAL-c498e-553d7374ee470e6942a43bbdfb762a4b6df3e0dea5413bd64098457c86fb96873</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27435,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33723144$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kanimozhi, Thirunavukkarasu</creatorcontrib><creatorcontrib>Hindu, Kalluru</creatorcontrib><creatorcontrib>Maheshvari, Yuvaraj</creatorcontrib><creatorcontrib>Khushnidha, Y</creatorcontrib><creatorcontrib>Kumaravel, Mahendrian</creatorcontrib><creatorcontrib>Srinivas, K</creatorcontrib><creatorcontrib>Manickavasagam, M</creatorcontrib><creatorcontrib>Mangathayaru, Kalachaveedu</creatorcontrib><title>Herbal supplement usage among cancer patients: A questionnaire-based survey</title><title>Journal of cancer research and therapeutics</title><addtitle>J Cancer Res Ther</addtitle><description>Background: Herbal supplements (HS) are one of the most commonly used complementary and alternative medicines in cancer. Reduced therapeutic efficacy of prescription anticancer agents through unwarranted herb-drug interactions is a major efficacy/safety concern. In view of the rising cancer prevalence in India along with a high degree of reliance and cultural acceptability in favor of traditional medicine drugs, prevalence data exclusively of HS usage during cancer treatment are of considerable epidemiological significance.
Methodology: This questionnaire-based prospective observational study aimed at estimating the prevalence of HS among cancer patients during treatment at our tertiary care medical center. Taken on a population of 220 patients within a period of 9 months, data were generated by a customized validated questionnaire and the same processed by IBM SPSS Statistics for Windows, version XXIV, Armonk, NY: IBM Corp. Differences between HS use and nonuse with respect to demographic, disease, and treatment characteristics were assessed by Chi-square test. For examining the latter variables as possible predictors of HS usage, they were entered into bivariate logistic regression with odds ratio and confidence intervals calculated for each.
Results: Out of 220 patients, 57 (26%) were HS users and 163 (74%) were nonusers. Majority of the users (42.1%) were on self-prepared folklore herbal medicine postdiagnosis of cancer (57.9%), the most common reason cited being symptom palliation (35.1%) on the advice of friends and family (64.9%). Fear of disapproval was the most common reason cited (68.4%) for not disclosing HS usage to the physician.
Conclusion: Chemotherapy and unemployment are predictors of HS usage, and there is a significant association between occupation status and HS usage. This first study on HS prevalence among South Indian population proposes the need for a more robust evidence base for understanding all aspects of HS use in cancer.</description><subject>Adult</subject><subject>Cancer</subject><subject>Cancer patients</subject><subject>Care and treatment</subject><subject>Dietary supplements</subject><subject>Dietary Supplements - statistics & numerical data</subject><subject>Employment - statistics & numerical data</subject><subject>Female</subject><subject>Health Knowledge, Attitudes, Practice</subject><subject>Humans</subject><subject>India</subject><subject>Male</subject><subject>Medicine, Botanic</subject><subject>Medicine, Herbal</subject><subject>Middle Aged</subject><subject>Neoplasms - drug therapy</subject><subject>Phytotherapy - methods</subject><subject>Prospective Studies</subject><subject>Questionnaires</subject><subject>Surveys</subject><subject>Surveys and Questionnaires - statistics & numerical data</subject><subject>Young Adult</subject><issn>0973-1482</issn><issn>1998-4138</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp1kUtv1DAURi0EokNhzwpFYp3Bjt_sRiOghUpIqKwt27kZZZrYwU466r_HZVoe0iAvbNnnu9dXB6HXBK8ZwfTd3qd5_Xn77doI0hiinqAV0VrVjFD1FK2wlrQmTDVn6EXOe4y5bBr1HJ1RKhtKGFuhLxeQnB2qvEzTACOEuVqy3UFlxxh2lbfBQ6omO_flKb-vNtWPBfLcxxBsn6B2NkNb0ukW7l6iZ50dMrx62M_R948frrcX9dXXT5fbzVXtmVZQc05bSSUDYBKD0KyxjDrXdk6KcnSi7SjgFiwvY7hWMKwV49Ir0TktlKTn6O2x7pTir9-YfVxSKC1Nw2kjuNSY_KF2dgDThy7Oyfqxz95sBOeaKSpxoeoT1A4CJDvEAF1frv_h1yf4sloYe38ygI8Bn2LOCTozpX606c4QbO4lmnuJ5i-JJfLmYb7FjdD-DjxaK8DlETjEYYaUb4blAMkU9ibEw38LG0KFOfo2j77pT9eCsUE</recordid><startdate>20210101</startdate><enddate>20210101</enddate><creator>Kanimozhi, Thirunavukkarasu</creator><creator>Hindu, Kalluru</creator><creator>Maheshvari, Yuvaraj</creator><creator>Khushnidha, Y</creator><creator>Kumaravel, Mahendrian</creator><creator>Srinivas, K</creator><creator>Manickavasagam, M</creator><creator>Mangathayaru, Kalachaveedu</creator><general>Wolters Kluwer India Pvt. 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Mangathayaru, Kalachaveedu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c498e-553d7374ee470e6942a43bbdfb762a4b6df3e0dea5413bd64098457c86fb96873</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Adult</topic><topic>Cancer</topic><topic>Cancer patients</topic><topic>Care and treatment</topic><topic>Dietary supplements</topic><topic>Dietary Supplements - statistics & numerical data</topic><topic>Employment - statistics & numerical data</topic><topic>Female</topic><topic>Health Knowledge, Attitudes, Practice</topic><topic>Humans</topic><topic>India</topic><topic>Male</topic><topic>Medicine, Botanic</topic><topic>Medicine, Herbal</topic><topic>Middle Aged</topic><topic>Neoplasms - drug therapy</topic><topic>Phytotherapy - methods</topic><topic>Prospective Studies</topic><topic>Questionnaires</topic><topic>Surveys</topic><topic>Surveys and Questionnaires - statistics & numerical data</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kanimozhi, Thirunavukkarasu</creatorcontrib><creatorcontrib>Hindu, Kalluru</creatorcontrib><creatorcontrib>Maheshvari, Yuvaraj</creatorcontrib><creatorcontrib>Khushnidha, Y</creatorcontrib><creatorcontrib>Kumaravel, Mahendrian</creatorcontrib><creatorcontrib>Srinivas, K</creatorcontrib><creatorcontrib>Manickavasagam, M</creatorcontrib><creatorcontrib>Mangathayaru, Kalachaveedu</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><jtitle>Journal of cancer research and therapeutics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kanimozhi, Thirunavukkarasu</au><au>Hindu, Kalluru</au><au>Maheshvari, Yuvaraj</au><au>Khushnidha, Y</au><au>Kumaravel, Mahendrian</au><au>Srinivas, K</au><au>Manickavasagam, M</au><au>Mangathayaru, Kalachaveedu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Herbal supplement usage among cancer patients: A questionnaire-based survey</atitle><jtitle>Journal of cancer research and therapeutics</jtitle><addtitle>J Cancer Res Ther</addtitle><date>2021-01-01</date><risdate>2021</risdate><volume>17</volume><issue>1</issue><spage>136</spage><epage>141</epage><pages>136-141</pages><issn>0973-1482</issn><eissn>1998-4138</eissn><abstract>Background: Herbal supplements (HS) are one of the most commonly used complementary and alternative medicines in cancer. Reduced therapeutic efficacy of prescription anticancer agents through unwarranted herb-drug interactions is a major efficacy/safety concern. In view of the rising cancer prevalence in India along with a high degree of reliance and cultural acceptability in favor of traditional medicine drugs, prevalence data exclusively of HS usage during cancer treatment are of considerable epidemiological significance.
Methodology: This questionnaire-based prospective observational study aimed at estimating the prevalence of HS among cancer patients during treatment at our tertiary care medical center. Taken on a population of 220 patients within a period of 9 months, data were generated by a customized validated questionnaire and the same processed by IBM SPSS Statistics for Windows, version XXIV, Armonk, NY: IBM Corp. Differences between HS use and nonuse with respect to demographic, disease, and treatment characteristics were assessed by Chi-square test. For examining the latter variables as possible predictors of HS usage, they were entered into bivariate logistic regression with odds ratio and confidence intervals calculated for each.
Results: Out of 220 patients, 57 (26%) were HS users and 163 (74%) were nonusers. Majority of the users (42.1%) were on self-prepared folklore herbal medicine postdiagnosis of cancer (57.9%), the most common reason cited being symptom palliation (35.1%) on the advice of friends and family (64.9%). Fear of disapproval was the most common reason cited (68.4%) for not disclosing HS usage to the physician.
Conclusion: Chemotherapy and unemployment are predictors of HS usage, and there is a significant association between occupation status and HS usage. This first study on HS prevalence among South Indian population proposes the need for a more robust evidence base for understanding all aspects of HS use in cancer.</abstract><cop>India</cop><pub>Wolters Kluwer India Pvt. Ltd</pub><pmid>33723144</pmid><doi>10.4103/jcrt.JCRT_612_18</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adult Cancer Cancer patients Care and treatment Dietary supplements Dietary Supplements - statistics & numerical data Employment - statistics & numerical data Female Health Knowledge, Attitudes, Practice Humans India Male Medicine, Botanic Medicine, Herbal Middle Aged Neoplasms - drug therapy Phytotherapy - methods Prospective Studies Questionnaires Surveys Surveys and Questionnaires - statistics & numerical data Young Adult |
| title | Herbal supplement usage among cancer patients: A questionnaire-based survey |
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