Continuous synthesis of 1‐ethoxy‐2,3‐difluoro‐4‐iodo‐benzene in a microreactor system and the Gaussian and computational fluid dynamics simulations

A microreactor system consisting of membrane‐dispersion tube‐in‐tube microreactors and delay loops was developed for the continuous synthesis of 1‐ethoxy‐2,3‐difluoro‐4‐iodo‐benzene. Because of the high mass and heat transfer in the microreactor system, ortho‐ and halogen‐lithiation could be perform...

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