Small iron oxide nanoparticles as MRI T1 contrast agent: scalable inexpensive water-based synthesis using a flow reactor

Small iron oxide nanoparticles as MRI T1 contrast agent: scalable inexpensive water-based synthesis using a flow reactor

Small iron oxide nanoparticles (IONPs) were synthesised in water via co-precipitation by quenching particle growth after the desired magnetic iron oxide phase formed. This was achieved in a millifluidic multistage flow reactor by precisely timed addition of an acidic solution. IONPs (

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Veröffentlicht in:Nanoscale 2021-01, Vol.13 (19), p.8795-8805
Hauptverfasser: Besenhard, Maximilian O., Panariello, Luca, Kiefer, Celine, LaGrow, Alec P., Storozhuk, Liudmyla, Perton, Francis, Begin, Sylvie, Mertz, Damien, Nguyen Thi Kim Thanh, Gavriilidis, Asterios
Format: Artikel
Sprache:eng
Schlagworte:
Chemistry
Chemistry, Multidisciplinary
Contrast agents
Coprecipitation
Dextrans
Gadolinium
High temperature
Iron oxides
Magnetic resonance imaging
Materials Science
Materials Science, Multidisciplinary
Nanoparticles
Nanoscience & Nanotechnology
Physical Sciences
Physics
Physics, Applied
Quenching
Reagents
Science & Technology
Science & Technology - Other Topics
Synthesis
Technology
Temperature control
Temperature effects
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Zusammenfassung:Small iron oxide nanoparticles (IONPs) were synthesised in water via co-precipitation by quenching particle growth after the desired magnetic iron oxide phase formed. This was achieved in a millifluidic multistage flow reactor by precisely timed addition of an acidic solution. IONPs (
ISSN:2040-3364
2040-3372
DOI:10.1039/d1nr00877c