Synthesis, in vitro cytotoxic and apoptotic effects, and molecular docking study of novel adamantane derivatives

[4‐(Adamantane‐1‐carboxamido)‐3‐oxo‐1‐thia‐4‐azaspiro[4.4]nonan‐2‐yl]acetic acid (4a) and [4‐(adamantane‐1‐carboxamido)‐8‐nonsubstituted/substituted‐3‐oxo‐1‐thia‐4‐azas‐piro[4.5]decane‐2‐yl]acetic acid (4b–g) derivatives were synthesized; their structures were verified by elemental analysis, infrare...

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Veröffentlicht in:	Archiv der Pharmazie (Weinheim) 2021-05, Vol.354 (5), p.e2000256-n/a
Hauptverfasser:	Turk‐Erbul, Basak, Karaman, Ecem F., Duran, Gizem N., Ozbil, Mehmet, Ozden, Sibel, Goktas, Fusun
Format:	Artikel
Sprache:	eng
Schlagworte:	antitumor activity Apoptosis cytotoxic activity Cytotoxicity NMR Nuclear magnetic resonance Spectrum analysis structure elucidation synthesis thiazolidine
Online-Zugang:	Volltext
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