Inhibitory Circuits in the Basolateral Amygdala in Aversive Learning and Memory

Neural circuits in the basolateral amygdala (BLA) play a pivotal role in the learning and memory formation, and processing of emotionally salient experiences, particularly aversive ones. A diverse population of GABAergic neurons present in the BLA orchestrate local circuits to mediate emotional memo...

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Veröffentlicht in:Frontiers in neural circuits 2021-04, Vol.15, p.633235-633235, Article 633235
Hauptverfasser: Perumal, Madhusoothanan B., Sah, Pankaj
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Sprache:eng
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Zusammenfassung:Neural circuits in the basolateral amygdala (BLA) play a pivotal role in the learning and memory formation, and processing of emotionally salient experiences, particularly aversive ones. A diverse population of GABAergic neurons present in the BLA orchestrate local circuits to mediate emotional memory functions. Targeted manipulation of GABAergic neuronal subtypes has shed light on cell-type specific functional roles in the fear learning and memory, revealing organizing principles for the operation of inhibitory circuit motifs in the BLA.
ISSN:1662-5110
1662-5110
DOI:10.3389/fncir.2021.633235