Combined 1-Deoxynojirimycin and Ibuprofen Treatment Decreases Microglial Activation, Phagocytosis and Dopaminergic Degeneration in MPTP-Treated Mice

Inflammation is a predominant aspect of neurodegenerative diseases and experimental studies performed in animal models of Parkinson’s disease (PD) suggesting that a sustained neuroinflammation exacerbates the nigrostriatal degeneration pathway. The central role of microglia in neuroinflammation has...

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Veröffentlicht in:	Journal of neuroimmune pharmacology 2021-06, Vol.16 (2), p.390-402
Hauptverfasser:	Costa, TCS, Fernandez-Villalba, E, Izura, V., Lucas-Ochoa, AM, Menezes-Filho, NJ, Santana, RC, de Oliveira, MD, Araújo, FM, Estrada, C, Silva, VDA, Costa, SL, Herrero, MT
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedicine Cell Biology Cytokines Immunology Neurosciences Nonsteroidal anti-inflammatory drugs Original Article Parkinson's disease Pharmacology/Toxicology Virology
Online-Zugang:	Volltext
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