Transcriptional profiling reveals potential involvement of microvillous TRPM5-expressing cells in viral infection of the olfactory epithelium

Background Understanding viral infection of the olfactory epithelium is essential because the olfactory nerve is an important route of entry for viruses to the central nervous system. Specialized chemosensory epithelial cells that express the transient receptor potential cation channel subfamily M m...

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Veröffentlicht in:	BMC genomics 2021-03, Vol.22 (1), p.224-224, Article 224
Hauptverfasser:	Baxter, B. Dnate', Larson, Eric D., Merle, Laetitia, Feinstein, Paul, Polese, Arianna Gentile, Bubak, Andrew N., Niemeyer, Christy S., Hassell, James, Shepherd, Doug, Ramakrishnan, Vijay R., Nagel, Maria A., Restrepo, Diego
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biotechnology & Applied Microbiology Central nervous system Chemoreception Depth profiling Development and progression Epithelial cells Epithelium Flow cytometry Gene expression Genetic aspects Genetic transcription Genetics & Heredity Genomics Health aspects Immunity Infections Inflammation Inflammatory response Intestine Ion channels Life Sciences Life Sciences & Biomedicine Medical research Medicine, Experimental Mice Mice, Inbred C57BL Mice, Transgenic Microvillous cells Mouse Neurons Olfactory epithelium Olfactory marker protein Olfactory Mucosa Olfactory nerve Olfactory Receptor Neurons Olfactory sensory neurons Ontology Proteins Science & Technology Sensory neurons Transcription Transcriptomes Transgenic mice Transient receptor potential proteins TRPM Cation Channels - genetics Viral infection Viral infections Virus Diseases
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