Citrullyl-Hydroxyprolyl-Proline (ChPP): An Artificially Synthesized Tripeptide as Potent ACE Inhibitor

Currently bioactive peptides are the main focus in attempts to identify novel angiotensin-converting enzyme inhibitors (ACEIs) for the treatment of hypertension due to their fewer side effects. In the present study we aimed to investigate the antihypertensive activity of 4 synthetic tripeptides Orni...

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Veröffentlicht in:	International journal of peptide research and therapeutics 2021-06, Vol.27 (2), p.967-976
Hauptverfasser:	Qian, Bingjun, Yu, Lili, Tian, Chongchong, Huang, Siyi, Huo, Jianghua, Villarreal, Oscar D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin Angiotensin II Angiotensin-converting enzyme inhibitors Animal Anatomy Antihypertensives Biochemistry Biomedical and Life Sciences Blood pressure Histology Hydrogen bonding Hydroxyproline Hypertension Life Sciences Molecular Medicine Morphology Oral administration Peptidyl-dipeptidase A Pharmaceutical Sciences/Technology Pharmacology/Toxicology Polymer Sciences Proline Spectrophotometry
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