Role of Caspase-3, IL-1β and oxidative stress in Iraqi women with breast cancer

Role of Caspase-3, IL-1β and oxidative stress in Iraqi women with breast cancer

Breast Cancer is caused by malignant tissue cells and has become one of the world’s biggest medical problems. The goal of this research was to determine the serum concentration of markers of oxidative stress that play an important role in the multiple factors involved in breast cancer development, g...

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Veröffentlicht in:Journal of physics. Conference series 2021-03, Vol.1853 (1), p.12050
Hauptverfasser: Al-Musawi, A K, Al-Rubae’i, S H N, Mahdi, M F
Format: Artikel
Sprache:eng
Schlagworte:
Apoptosis
Breast cancer
Lipid peroxidation
Lipids
Medical research
Oxidative stress
Physics
Risk analysis
Tumors
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Zusammenfassung:Breast Cancer is caused by malignant tissue cells and has become one of the world’s biggest medical problems. The goal of this research was to determine the serum concentration of markers of oxidative stress that play an important role in the multiple factors involved in breast cancer development, growth, and invasion. Serum of 90 women patients (45 breast cancer and 45 benign breast tumors) and 42 healthy individuals as control group were used in this study. Serum level of MDA, PC, 8-OHdG, IL-1β and Caspase-3 were measured by ELISA. Highly significantly increased levels (p
ISSN:1742-6588
1742-6596
DOI:10.1088/1742-6596/1853/1/012050