Association between ambient temperature and serum uric acid in autumn and winter in Guangdong Province

[Background] Previous studies have reported seasonal variation in serum uric acid, and a higher hyperglycemia risk is observed in workers exposed to high temperature. However, there is limited evidence on the acute effect of temperature exposure on serum uric acid among general population. [Objective] This study estimates the association between temperature exposure and serum uric acid, and provides evidence for disease prevention and control. [Methods] From October 2015 to February 2016, a multi-stage cluster sampling method was adopted to select study subjects from the Guangdong Provincial Residents' Chronic Disease and Nutrition Monitoring Survey, and retrieved their socioeconomic characteristics, health status, dietary status, physical fitness, and laboratory test information. Meteorological data including daily mean temperature (MT) and relative humidity (RH) in 698 monitoring stations across China were collected from the China Meteorological Science Data Sharing Service Platform. The Australian National