Telomere Length Change in a Multidomain Lifestyle Intervention to Prevent Cognitive Decline: A Randomized Clinical Trial

Abstract Background Shorter leukocyte telomere length (LTL) is associated with aging and dementia. Impact of lifestyle changes on LTL, and relation to cognition and genetic susceptibility for dementia, has not been investigated in randomized controlled trials (RCTs). Methods Finnish Geriatric Interv...

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Veröffentlicht in:	The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2021-03, Vol.76 (3), p.491-498
Hauptverfasser:	Sindi, Shireen, Solomon, Alina, Kåreholt, Ingemar, Hovatta, Iiris, Antikainen, Riitta, Hänninen, Tuomo, Levälahti, Esko, Laatikainen, Tiina, Lehtisalo, Jenni, Lindström, Jaana, Paajanen, Teemu, Peltonen, Markku, Singh Khalsa, Dharma, Wolozin, Benjamin, Strandberg, Timo, Tuomilehto, Jaakko, Soininen, Hilkka, Ngandu, Tiia, Kivipelto, Miia
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Apolipoprotein E Behavioral intervention Clinical trials Cognitive ability Dementia Dementia disorders Dementia prevention Executive function Intervention Long term memory Older adults Older people Polymerase chain reaction Telomeres THE JOURNAL OF GERONTOLOGY: Medical Sciences
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