Hypericum ascyron L. extract reduces particulate matter‐induced airway inflammation in mice

The consequences of increased industrialization increased the risk of asthma and breathing difficulties due to increased particulate matter in the air. We aim to investigate the therapeutic properties of Hypericum ascyron L. extract (HAE) in airway inflammation and unravel its mechanism of action. W...

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Veröffentlicht in:	Phytotherapy research 2021-03, Vol.35 (3), p.1621-1633
Hauptverfasser:	Lee, Yuan Yee, Yang, Won‐Kyung, Han, Jee Eun, Kwak, Dongmi, Kim, Tae‐Hwan, Saba, Evelyn, Kim, Sung‐Dae, Lee, Young‐Cheol, Kim, Jong Sung, Kim, Seung‐Hyung, Rhee, Man Hee
Format:	Artikel
Sprache:	eng
Schlagworte:	airway inflammation Alveoli Animal tissues Animals Asthma Biocompatibility Bronchus Cell viability Cytokines Cytotoxicity Diesel engines diesel particulate matter Disease Models, Animal fine dust Fly ash Gene expression Health risks Hypericum - chemistry Hypericum ascyron Hypericum ascyron L Immune system In vivo methods and tests Inflammation Inflammation - chemically induced Inflammation - drug therapy Inflammatory response Leukocytes (neutrophilic) Lungs Lymphocytes Lymphocytes T MAP kinase MH‐S Mice NF-κB protein Nitric oxide Particulate matter Particulate Matter - chemistry Respiratory tract Respiratory tract diseases Toxicity Tumor necrosis factor
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