Quinoline‐Proline, Triazole Hybrids: Design, Synthesis, Antituberculosis, Molecular Docking, and ADMET Studies

A series of novel quinoline‐proline hybrids (11a‐g) and quinoline‐proline‐1,2,3‐triazole hybrids (12‐14) were synthesized by click chemistry based on molecular hybridization concept and were characterized by NMR, mass spectrometry, and elemental analysis. All the titled target compounds were tested...

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Veröffentlicht in:	Journal of heterocyclic chemistry 2021-04, Vol.58 (4), p.952-968
Hauptverfasser:	Ganesan, Moorthiamma Sarathy, Raja, Kamatchi Kanmani, Murugesan, Sankaranarayanan, Karankumar, Banoth, Faheem, Faheem, Thirunavukkarasu, Sappanimuthu, Shetye, Gauri, Ma, Rui, Franzblau, Scott G., Wan, Baojie, Rajagopal, Gurusamy
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemical synthesis In vitro methods and tests Mass spectrometry Molecular docking NMR Nuclear magnetic resonance Organic compounds Proline Quinoline Toxicity Triazoles Tuberculosis
Online-Zugang:	Volltext
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