70-gene signature as an aid for treatment decisions in early breast cancer: updated results of the phase 3 randomised MINDACT trial with an exploratory analysis by age

The MINDACT trial showed excellent 5-year distant metastasis-free survival of 94·7% (95% CI 92·5–96·2) in patients with breast cancer of high clinical and low genomic risk who did not receive chemotherapy. We present long-term follow-up results together with an exploratory analysis by age. MINDACT w...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The lancet oncology 2021-04, Vol.22 (4), p.476-488
Hauptverfasser:	Piccart, Martine, van 't Veer, Laura J, Poncet, Coralie, Lopes Cardozo, Josephine M N, Delaloge, Suzette, Pierga, Jean-Yves, Vuylsteke, Peter, Brain, Etienne, Vrijaldenhoven, Suzan, Neijenhuis, Peter A, Causeret, Sylvian, Smilde, Tineke J, Viale, Giuseppe, Glas, Annuska M, Delorenzi, Mauro, Sotiriou, Christos, Rubio, Isabel T, Kümmel, Sherko, Zoppoli, Gabriele, Thompson, Alastair M, Matos, Erika, Zaman, Khalil, Hilbers, Florentine, Fumagalli, Debora, Ravdin, Peter, Knox, Susan, Tryfonidis, Konstantinos, Peric, Aleksandra, Meulemans, Bart, Bogaerts, Jan, Cardoso, Fatima, Rutgers, Emiel J T
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age Age Factors Aged Anthracycline Anthracyclines - administration & dosage Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - genetics Breast Neoplasms - pathology Bridged-Ring Compounds - administration & dosage Cancer therapies Chemotherapy Clinical decision making Clinical trials Cytotoxicity Decision making Disease-Free Survival Endocrine therapy ErbB-2 protein Female Gene expression Gene Expression Regulation, Neoplastic - drug effects Genomics Humans Hypotheses Invasiveness Lymph nodes Lymphatic system Medical prognosis Metastases Metastasis Middle Aged Neoplasm Metastasis Patients Population studies Reproductive status Survival Taxoids - administration & dosage Transcriptome - genetics Treatment Outcome Tumors Womens health Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!