Stereotactic radiotherapy and oligometastases – Authors' reply

Regarding the so-called missed opportunity and the potential effect of our study on recruitment for randomised controlled trials, we note that the Commissioning through Evaluation programme prepared 17 stereotactic ablative radiotherapy centres across the UK to recruit patients into the CORE trial (...

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Veröffentlicht in:The lancet oncology 2021-04, Vol.22 (4), p.e133-e133
Hauptverfasser: Chalkidou, Anastasia, Patrick, Hannah, Hatton, Matthew Q, Hawkins, Maria A, van As, Nicholas
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container_end_page e133
container_issue 4
container_start_page e133
container_title The lancet oncology
container_volume 22
creator Chalkidou, Anastasia
Patrick, Hannah
Hatton, Matthew Q
Hawkins, Maria A
van As, Nicholas
description Regarding the so-called missed opportunity and the potential effect of our study on recruitment for randomised controlled trials, we note that the Commissioning through Evaluation programme prepared 17 stereotactic ablative radiotherapy centres across the UK to recruit patients into the CORE trial (NCT02759783) via its Radiotherapy Trials Quality Assurance process. There are other relevant ongoing randomised controlled trials, such as four phase 3 randomised controlled trials for oligometastatic prostate cancer alone.2 In the meantime, careful patient selection by experienced multi-disciplinary teams remains essential to ensure that only patients who are likely to benefit from stereotactic ablative radiotherapy receive this treatment. HP reports working for the UK National Institute for Health and Care Excellence during the conduct of the study, which was commissioned by the UK National Health Service England to manage the Commissioning through Evaluation project.
doi_str_mv 10.1016/S1470-2045(21)00144-3
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source MEDLINE; ScienceDirect Journals (5 years ago - present); ProQuest Central UK/Ireland
subjects Clinical trials
Humans
Neoplasms
Prospective Studies
Prostate cancer
Quality assurance
Radiation therapy
Radiosurgery - adverse effects
Registries
title Stereotactic radiotherapy and oligometastases – Authors' reply
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