Protective role of long noncoding RNA CRNDE in myocardial tissues from injury caused by sepsis through the microRNA-29a/SIRT1 axis

Aims: The associations between colorectal neoplasia differentially expressed (CRNDE), a novel long non-coding RNA (lncRNA), and inflammation and cell apoptosis have been underscored recently. However, its function in sepsis-induced myocardial injury remains undetermined. The current study sets to ex...

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Veröffentlicht in:	Life sciences (1973) 2020-08, Vol.255, p.1
Hauptverfasser:	Zhu, Yan, Sun, Aichen, Meng, Taocheng, Li, Haolan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal tissues Apoptosis Cardiomyocytes Caspase-3 Inflammation Injuries Lipopolysaccharides MicroRNAs miRNA NF-κB protein Non-coding RNA Phosphorylation Poly(ADP-ribose) polymerase Poly(ADP-ribose) Polymerase 1 Post-transcription Reactive oxygen species Ribonucleic acid RNA Sepsis SIRT1 protein
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