Long-chain fatty dihydropyridines: Docking calcium channel studies and antihypertensive activity

From the synthesis of 43 lipophilic dihydropyridines, the aim of this study was to verify whether the new dihydropyridines have calcium channel affinity using coupling studies and to determine antihypertensive and antioxidant properties, as well as toxicology and toxicity nifedipine and three new co...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Life sciences (1973) 2020-10, Vol.259, p.118210, Article 118210
Hauptverfasser:	Santa-Helena, Eduarda, Cabrera, Diego da Costa, D'Oca, Marcelo G. Montes, Scaini, João Luís Rheingantz, de Oliveira, Matheus William Bandeira, Werhli, Adriano Velasque, Machado, Karina dos Santos, Gonçalves, Carla Amorim Neves, Nery, Luiz Eduardo Maia
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antihypertensives Antioxidant - calcium channel blocker Antioxidants Arginine Blood pressure Calcium Creatine Creatine kinase DHP-antihypertensive Docking Heart rate Hypertension Kinases Lipid peroxidation Lipids Lipophilic Nifedipine Oxidative stress Peroxidation Reactive oxygen species Tachycardia Toxicity Toxicology Urea
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!