Programming Escherichia coli to function as a digital display

Synthetic genetic circuits offer the potential to wield computational control over biology, but their complexity is limited by the accuracy of mathematical models. Here, we present advances that enable the complete encoding of an electronic chip in the DNA carried by Escherichia coli ( E. coli ). Th...

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Veröffentlicht in:	Molecular systems biology 2020-03, Vol.16 (3), p.e9401-n/a, Article 9401
Hauptverfasser:	Shin, Jonghyeon, Zhang, Shuyi, Der, Bryan S, Nielsen, Alec AK, Voigt, Christopher A
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Approximation Artificial Intelligence Automation Biochemistry & Molecular Biology Biology Calculators Circuits Clocks Computer applications Computer Storage Devices Deoxyribonucleic acid design automation DNA E coli EMBO10 EMBO41 Equipment Design Escherichia coli Escherichia coli - genetics Fluorescence genetic circuits Life Sciences & Biomedicine logic gates Mathematical models Model accuracy Regulators Repressors RNA polymerase Science & Technology Segments Sensors Signal Processing, Computer-Assisted - instrumentation Software synthetic biology Synthetic Biology - instrumentation
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