Synthesis, Biological Evaluation, Molecular Docking, ADME Predictions and QSAR Studies of Novel 1,2-Diazet and Pyrrole Derivatives as Anti-Inflammatory Agents

Here we synthesized novel 1, 2-diazet and pyrrole derivatives and screened for their anti-inflammatory activity. In vivo anti-inflammatory evaluation results revealed that compounds ( XVI ), ( XIV ) and ( XI ) exhibited the highest anti-inflammatory potencies all over the 4 hours, while compounds (...

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Veröffentlicht in:	Russian journal of bioorganic chemistry 2021, Vol.47 (1), p.183-198
Hauptverfasser:	El-Serwy, Walaa S., El-Serwy, Weam S., Mohamed, Neama A., Kassem, Emad M. M., Mostafa, Rasha E., Mohamed, Hanaa S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Chemical synthesis Kinases Life Sciences Molecular docking Organic Chemistry
Online-Zugang:	Volltext
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