Mass-spectrometry-based proteomic correlates of grade and stage reveal pathways and kinases associated with aggressive human cancers

Proteomic signatures associated with clinical measures of more aggressive cancers could yield molecular clues as to disease drivers. Here, utilizing the Clinical Proteomic Tumor Analysis Consortium (CPTAC) mass-spectrometry-based proteomics datasets, we defined differentially expressed proteins and...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Oncogene 2021-03, Vol.40 (11), p.2081-2095
Hauptverfasser:	Monsivais, Diana, Vasquez, Yasmin M., Chen, Fengju, Zhang, Yiqun, Chandrashekar, Darshan S., Faver, John C., Masand, Ramya P., Scheurer, Michael E., Varambally, Sooryanarayana, Matzuk, Martin M., Creighton, Chad J.
Format:	Artikel
Sprache:	eng
Schlagworte:	13/89 631/61/475 631/67/69 82/58 82/80 Adenocarcinoma Apoptosis Biochemistry & Molecular Biology Breast cancer Cancer Carcinogenesis Cell Biology Cell Cycle Proteins - genetics Colon Colon cancer Copy number Endometrial cancer Endometrium Female Gene expression Gene Expression Regulation, Neoplastic - genetics Genetic aspects Genetic transcription Genetics & Heredity Glioma Health aspects Human Genetics Humans Internal Medicine Kinases Life Sciences & Biomedicine Lung cancer Male MAP Kinase Kinase Kinase 2 - genetics Mass spectrometry Medicine Medicine & Public Health Microtubule-Associated Proteins - genetics Neoplasm Grading - classification Neoplasm Staging - classification Neoplasms - classification Neoplasms - genetics Neoplasms - pathology Observations Oncology Patients Phosphoproteins Phosphoproteins - genetics Phosphorylation Phosphotransferases - classification Phosphotransferases - genetics Protein kinase Protein Serine-Threonine Kinases - genetics Protein-Tyrosine Kinases - genetics Proteins Proteomics Science & Technology Scientific imaging Spectrometry Transcriptome - genetics Uterine cancer Uterus
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!