A novel 8.7-kb mitochondrial genome deletion accurately detects endometriosis in the plasma of symptomatic women

To evaluate an 8.7-kb mitochondrial DNA (mtDNA) deletion as a potential biomarker of endometriosis. We tested the diagnostic accuracy of the 8.7-kb deletion real-time PCR assay using 182 prospectively collected blood samples from females presenting with symptoms of endometriosis in a case–control fo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biomarkers in medicine 2020-02, Vol.14 (2), p.97-107
Hauptverfasser:	Harbottle, Andrew, Maggrah, Andrea, Usher, Robert, Desa, Elise, Creed, Jennifer M
Format:	Artikel
Sprache:	eng
Schlagworte:	Accuracy Adult Asymptomatic biomarker Biomarkers Deoxyribonucleic acid diagnostic accuracy Disease DNA DNA deletion DNA, Mitochondrial - genetics Endocrine therapy Endometriosis Endometriosis - blood Endometriosis - diagnosis Endometriosis - genetics Female Genome, Mitochondrial - genetics Genomes High-Throughput Nucleotide Sequencing Humans Infertility Laparoscopy Menstrual cycle Menstruation Mitochondrial DNA molecular diagnostic mtDNA Ovarian cancer Pain Patients Plasma Polymerase Chain Reaction Prospective Studies Quality control real-time PCR Sensitivity and Specificity Sequence Deletion Software Standard deviation Statistical analysis Womens health
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!