Selective inhibition of Zophobas morio (Coleoptera: Tenebrionidae) luciferase‐like enzyme luminescence by diclofenac and potential suitability for light‐off biosensing

The accumulation of toxic carboxylic compounds may cause severe effects on the environment and living organisms. A luciferase‐like enzyme, previously cloned from the Malpighian tubules of the non‐luminescent Zophobas morio mealworm, displays thioesterification activity with a wide range of carboxyli...

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Veröffentlicht in:	Luminescence (Chichester, England) England), 2021-03, Vol.36 (2), p.367-376
Hauptverfasser:	Carvalho, Mariele C., Tomazini, Atílio, Prado, Rogilene A., Viviani, Vadim R.
Format:	Artikel
Sprache:	eng
Schlagworte:	ATP Binding sites Biocompatibility Biosensors Carboxylic acids Coenzyme A Coenzymes Detoxification Diclofenac Drug development Environmental effects Enzymes Fireflies Inflammation luciferase‐like enzyme Luciferin Luminescence Malpighian tubules Nonsteroidal anti-inflammatory drugs Pollutants Substrates Thioesterification toxicity Zophobas morio
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