Parkinson’s Disease Master Regulators on Substantia Nigra and Frontal Cortex and Their Use for Drug Repositioning

Parkinson’s disease (PD) is among the most prevalent neurodegenerative diseases. Available evidences support the view of PD as a complex disease, being the outcome of interactions between genetic and environmental factors. In face of diagnosis and therapy challenges, and the elusive PD etiology, the...

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Veröffentlicht in:	Molecular neurobiology 2021-04, Vol.58 (4), p.1517-1534
Hauptverfasser:	Vargas, D. M., De Bastiani, M. A., Parsons, R. B., Klamt, F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedicine Cell Biology Computational neuroscience Cortex (frontal) Disease Environmental factors Etiology Movement disorders Neural networks Neurobiology Neurodegenerative diseases Neurology Neurosciences Parkinson's disease Substantia nigra Therapeutic applications Transcription factors Tubocurarine
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