Single-Center Results of Choledochal Cysts in Turkish Population
Choledochal cysts are seen commonly in Asian populations, but rarely in Western populations. The pathogenesis of these premalignant lesions is not fully understood yet and the risk of malignant transformation increases with age. The overall malignancy risk is 10%-15% in East Asian countries. In this...
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| Veröffentlicht in: | Archives of Iranian medicine 2021-01, Vol.24 (1), p.43-47 |
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| creator | Piskin, Erol Ustuner, Mehmet Akif Oter, Volkan Aydin, Osman Ozgun, Yigit Mehmet Colakoglu, Muhammet Kadri Aksoy, Erol Keklik, Tulay Temucin Ozogul, Yusuf Bayram Bostanci, Erdal Birol |
| description | Choledochal cysts are seen commonly in Asian populations, but rarely in Western populations. The pathogenesis of these premalignant lesions is not fully understood yet and the risk of malignant transformation increases with age. The overall malignancy risk is 10%-15% in East Asian countries. In this study, we aimed to present our surgical experience as a hepatobiliary center to the literature.
We retrospectively analyzed the data from the medical records of 70 patients operated for choledochal cyst between 2008-2019.
Sixty-two of the 70 (89%) patients were female and 8 (11%) were male, the mean age was 45.89 ± 15.32 years. Overall, 44 (63%) patients had type I (a+b+c), 20 (28%) type V (Caroli), 2 (3%) type II, 2 (3%) type III and 2 (3%) type IVb cysts. The most common operation was cyst excision combined with hepaticojejunostomy (n: 26, 37%). The median diameter of the resected cysts was 3 cm (min- max: 1-11 cm). Malignancy was observed only in three (4%) patients with type III, type Ib, and type V cyts, who were 19, 38, and 72 years old, respectively. Mortality was not observed, morbidity was determined totally in 30 (43%) cases during early and late postoperative periods.
Type of surgery in choledochal cysts differs according to the type of the cyst. Malignancy was observed at a rate of 4% in all age groups. Although the frequency of malignancy varies, the main treatment of choice should be surgery because malignancy can be seen at a young age. |
| doi_str_mv | 10.34172/aim.2021.07 |
| format | Article |
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We retrospectively analyzed the data from the medical records of 70 patients operated for choledochal cyst between 2008-2019.
Sixty-two of the 70 (89%) patients were female and 8 (11%) were male, the mean age was 45.89 ± 15.32 years. Overall, 44 (63%) patients had type I (a+b+c), 20 (28%) type V (Caroli), 2 (3%) type II, 2 (3%) type III and 2 (3%) type IVb cysts. The most common operation was cyst excision combined with hepaticojejunostomy (n: 26, 37%). The median diameter of the resected cysts was 3 cm (min- max: 1-11 cm). Malignancy was observed only in three (4%) patients with type III, type Ib, and type V cyts, who were 19, 38, and 72 years old, respectively. Mortality was not observed, morbidity was determined totally in 30 (43%) cases during early and late postoperative periods.
Type of surgery in choledochal cysts differs according to the type of the cyst. Malignancy was observed at a rate of 4% in all age groups. Although the frequency of malignancy varies, the main treatment of choice should be surgery because malignancy can be seen at a young age.</description><identifier>ISSN: 1029-2977</identifier><identifier>EISSN: 1735-3947</identifier><identifier>DOI: 10.34172/aim.2021.07</identifier><identifier>PMID: 33588567</identifier><language>eng</language><publisher>Iran: Academy of Medical Sciences of I.R. Iran</publisher><subject>Age groups ; Asian people ; Congenital diseases ; Cysts ; Epidemiology ; Gallbladder diseases ; Gastrointestinal surgery ; Pathogenesis ; Surgical outcomes</subject><ispartof>Archives of Iranian medicine, 2021-01, Vol.24 (1), p.43-47</ispartof><rights>2021 The Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</rights><rights>2021. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-f8cca0f9f462c9765e148dc101f3b0e3f363f5c5d0b5156de006f1c68b6bc3933</citedby><orcidid>0000-0002-6149-3000</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33588567$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Piskin, Erol</creatorcontrib><creatorcontrib>Ustuner, Mehmet Akif</creatorcontrib><creatorcontrib>Oter, Volkan</creatorcontrib><creatorcontrib>Aydin, Osman</creatorcontrib><creatorcontrib>Ozgun, Yigit Mehmet</creatorcontrib><creatorcontrib>Colakoglu, Muhammet Kadri</creatorcontrib><creatorcontrib>Aksoy, Erol</creatorcontrib><creatorcontrib>Keklik, Tulay Temucin</creatorcontrib><creatorcontrib>Ozogul, Yusuf Bayram</creatorcontrib><creatorcontrib>Bostanci, Erdal Birol</creatorcontrib><title>Single-Center Results of Choledochal Cysts in Turkish Population</title><title>Archives of Iranian medicine</title><addtitle>Arch Iran Med</addtitle><description>Choledochal cysts are seen commonly in Asian populations, but rarely in Western populations. The pathogenesis of these premalignant lesions is not fully understood yet and the risk of malignant transformation increases with age. The overall malignancy risk is 10%-15% in East Asian countries. In this study, we aimed to present our surgical experience as a hepatobiliary center to the literature.
We retrospectively analyzed the data from the medical records of 70 patients operated for choledochal cyst between 2008-2019.
Sixty-two of the 70 (89%) patients were female and 8 (11%) were male, the mean age was 45.89 ± 15.32 years. Overall, 44 (63%) patients had type I (a+b+c), 20 (28%) type V (Caroli), 2 (3%) type II, 2 (3%) type III and 2 (3%) type IVb cysts. The most common operation was cyst excision combined with hepaticojejunostomy (n: 26, 37%). The median diameter of the resected cysts was 3 cm (min- max: 1-11 cm). Malignancy was observed only in three (4%) patients with type III, type Ib, and type V cyts, who were 19, 38, and 72 years old, respectively. Mortality was not observed, morbidity was determined totally in 30 (43%) cases during early and late postoperative periods.
Type of surgery in choledochal cysts differs according to the type of the cyst. Malignancy was observed at a rate of 4% in all age groups. Although the frequency of malignancy varies, the main treatment of choice should be surgery because malignancy can be seen at a young age.</description><subject>Age groups</subject><subject>Asian people</subject><subject>Congenital diseases</subject><subject>Cysts</subject><subject>Epidemiology</subject><subject>Gallbladder diseases</subject><subject>Gastrointestinal surgery</subject><subject>Pathogenesis</subject><subject>Surgical outcomes</subject><issn>1029-2977</issn><issn>1735-3947</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNo9kEtLw0AUhQdRbK3uXEvAral3cueR7JTgCwqK1vWQTGZsapqJM8mi_95oq6t7uHycAx8h5xTmyKhMrot6M08goXOQB2RKJfIYMyYPxwxJFieZlBNyEsIagCGneEwmiDxNuZBTcvNWtx-NiXPT9sZHryYMTR8iZ6N85RpTOb0qmijfhvFZt9Fy8J91WEUvrhuaoq9de0qObNEEc7a_M_J-f7fMH-PF88NTfruINXLZxzbVugCbWSYSnUnBDWVppSlQiyUYtCjQcs0rKDnlojIAwlIt0lKUGjPEGbnc9XbefQ0m9GrtBt-OkyphGWcUONCRutpR2rsQvLGq8_Wm8FtFQf3qUqMu9aNLgRzxi33pUG5M9Q__-cFvOMJk1g</recordid><startdate>20210101</startdate><enddate>20210101</enddate><creator>Piskin, Erol</creator><creator>Ustuner, Mehmet Akif</creator><creator>Oter, Volkan</creator><creator>Aydin, Osman</creator><creator>Ozgun, Yigit Mehmet</creator><creator>Colakoglu, Muhammet Kadri</creator><creator>Aksoy, Erol</creator><creator>Keklik, Tulay Temucin</creator><creator>Ozogul, Yusuf Bayram</creator><creator>Bostanci, Erdal Birol</creator><general>Academy of Medical Sciences of I.R. 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The pathogenesis of these premalignant lesions is not fully understood yet and the risk of malignant transformation increases with age. The overall malignancy risk is 10%-15% in East Asian countries. In this study, we aimed to present our surgical experience as a hepatobiliary center to the literature.
We retrospectively analyzed the data from the medical records of 70 patients operated for choledochal cyst between 2008-2019.
Sixty-two of the 70 (89%) patients were female and 8 (11%) were male, the mean age was 45.89 ± 15.32 years. Overall, 44 (63%) patients had type I (a+b+c), 20 (28%) type V (Caroli), 2 (3%) type II, 2 (3%) type III and 2 (3%) type IVb cysts. The most common operation was cyst excision combined with hepaticojejunostomy (n: 26, 37%). The median diameter of the resected cysts was 3 cm (min- max: 1-11 cm). Malignancy was observed only in three (4%) patients with type III, type Ib, and type V cyts, who were 19, 38, and 72 years old, respectively. Mortality was not observed, morbidity was determined totally in 30 (43%) cases during early and late postoperative periods.
Type of surgery in choledochal cysts differs according to the type of the cyst. Malignancy was observed at a rate of 4% in all age groups. Although the frequency of malignancy varies, the main treatment of choice should be surgery because malignancy can be seen at a young age.</abstract><cop>Iran</cop><pub>Academy of Medical Sciences of I.R. Iran</pub><pmid>33588567</pmid><doi>10.34172/aim.2021.07</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0002-6149-3000</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | Archives of Iranian medicine, 2021-01, Vol.24 (1), p.43-47 |
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| subjects | Age groups Asian people Congenital diseases Cysts Epidemiology Gallbladder diseases Gastrointestinal surgery Pathogenesis Surgical outcomes |
| title | Single-Center Results of Choledochal Cysts in Turkish Population |
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