Synthesis, Physicochemical Properties, Drug Likeness, and Antitumor Activity of 2-[5-(4-Bromobenzylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-methylbutanoic Acid Esters and Amides

2-[5-(4-Bromobenzylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-methylbutanoyl chloride was reacted with ethanol and amines to obtain the corresponding ester and amides, and their physicochemical properties and drug likeness were predicted in silico. The synthesized compounds were evaluated...

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Veröffentlicht in:	Russian journal of organic chemistry 2021, Vol.57 (1), p.25-31
Hauptverfasser:	Horishny, V. Ya, Matiychuk, V. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amides Amines Anticancer properties Biotechnology Cancer Chemistry Chemistry and Materials Science Esters Ethanol Leukemia Organic Chemistry
Online-Zugang:	Volltext
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