Blood testis barrier revisited—Analysis of post‐chemotherapy germ cell tumor orchidectomy and retroperitoneal lymph node dissection specimens

Objective To assess the response of chemotherapy on the primary tumor, compare it with the response in retroperitoneal disease, and study factors associated with pathological complete response. Methods We conducted a retrospective audit of all high inguinal orchidectomies (HIOs) performed after chem...

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Veröffentlicht in:	Journal of surgical oncology 2021-03, Vol.123 (4), p.1157-1163
Hauptverfasser:	Gupta, Amit, Noronha, Jarin, Bakshi, Ganesh, Menon, Santosh, Pal, Mahendra, Joshi, Amit, Prabash, Kumar, Noronha, Vanita, Murthy, Vedang, Krishnattry, Rahul, Patil, Akshay, Prakash, Gagan J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Antineoplastic Combined Chemotherapy Protocols - therapeutic use Blood-Testis Barrier - drug effects Blood-Testis Barrier - metabolism Chemotherapy Combined Modality Therapy Female Follow-Up Studies germ cell tumor Humans India Lymph Node Excision - methods Lymph Nodes - pathology Lymph Nodes - surgery Lymphatic system Male Middle Aged neoadjuvant chemotherapy Neoplasm, Residual - drug therapy Neoplasm, Residual - pathology Neoplasm, Residual - surgery Neoplasms, Germ Cell and Embryonal - drug therapy Neoplasms, Germ Cell and Embryonal - pathology Neoplasms, Germ Cell and Embryonal - surgery orchidectomy Orchiectomy - methods pathological complete response Prognosis Prospective Studies retroperitoneal lymph node dissection Retroperitoneal Neoplasms - drug therapy Retroperitoneal Neoplasms - pathology Retroperitoneal Neoplasms - surgery Retrospective Studies Young Adult
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