Aescin - a natural soap for the formation of lipid nanodiscs with tunable size

The saponin β-aescin from the seed extract of the horse chestnut tree Aesculus hippocastanum has demonstrated a beneficial role in clinical therapy which is in part related to its strong interaction with biological membranes. In this context the present work investigates the self-assembly of nm-size...

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Veröffentlicht in:	Soft matter 2021-02, Vol.17 (7), p.1888-19
Hauptverfasser:	Geisler, Ramsia, Pedersen, Martin Cramer, Preisig, Natalie, Hannappel, Yvonne, Prévost, Sylvain, Dattani, Rajeev, Arleth, Lise, Hellweg, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological membranes Electron microscopy Freeze-fracture Lipids Nanoparticles Phase transitions Phosphocholine Phospholipids Saponins Self-assembly Sheets Small angle X ray scattering Strong interactions (field theory) X-ray scattering
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