FRAGMENTED QRS, AS A SURROGATE MARKER FOR MYOCARDIAL FIBROSIS, IS ASSOCIATED WITH HIGH BLOOD LEAD LEVELS
Lead exposure is a serious environmental problem and associated with serious health prob- lems. Blood lead levels should be measured especially in lead exposed workers. Lead exposure could cause myocardial fibrosis and scar in cardiac tissue. Fragmented QRS (fQRS) is an easy to detect electrocardiog...
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| Veröffentlicht in: | Fresenius environmental bulletin 2020-12, Vol.29 (12A), p.11501 |
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| creator | Karanfil, Mustafa Gunduzoz, Meside Karakurt, Murat Arugarslan, Emre Unal, Sefa Akbuga, Kursat Akdi, Ahmet Erdol, Mehmet Akif Yayla, Kadriye Gayretli Ertem, Ahmet Goktug Ozeke, Ozcan Yayla, Cagri |
| description | Lead exposure is a serious environmental problem and associated with serious health prob- lems. Blood lead levels should be measured especially in lead exposed workers. Lead exposure could cause myocardial fibrosis and scar in cardiac tissue. Fragmented QRS (fQRS) is an easy to detect electrocardiography (ECG) finding and a predictor of myocardial scar. In this study we aimed to investigate the association of fQRS and lead exposure One hundred and fourty five occupationally lead exposed male workers with high blood lead levels and 158 male workers with normal blood lead levels are retrospectively evaluated. Hematological, echocardiography and ECG findings were compared. Workers with high blood lead level had significantly higher fQRS than workers with normal blood lead levels (13.8%, 4.4%, respectively, p: 0.004) In regression analysis, blood lead level is associated with fQRS (1.026( 1.011 -1.041), p=0.001). In this study, we found that workers with high blood lead levels has higher fQRS compared with workers with normal blood lead levels. fQRS could be a surrogated marker for suspicion for high blood lead. Further prospective and randomized trials is needed for this relationship. |
| format | Article |
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Blood lead levels should be measured especially in lead exposed workers. Lead exposure could cause myocardial fibrosis and scar in cardiac tissue. Fragmented QRS (fQRS) is an easy to detect electrocardiography (ECG) finding and a predictor of myocardial scar. In this study we aimed to investigate the association of fQRS and lead exposure One hundred and fourty five occupationally lead exposed male workers with high blood lead levels and 158 male workers with normal blood lead levels are retrospectively evaluated. Hematological, echocardiography and ECG findings were compared. Workers with high blood lead level had significantly higher fQRS than workers with normal blood lead levels (13.8%, 4.4%, respectively, p: 0.004) In regression analysis, blood lead level is associated with fQRS (1.026( 1.011 -1.041), p=0.001). In this study, we found that workers with high blood lead levels has higher fQRS compared with workers with normal blood lead levels. fQRS could be a surrogated marker for suspicion for high blood lead. Further prospective and randomized trials is needed for this relationship.</description><identifier>ISSN: 1018-4619</identifier><identifier>EISSN: 1610-2304</identifier><language>eng</language><publisher>Freising: Parlar Scientific Publications</publisher><subject>Blood ; Blood levels ; Echocardiography ; EKG ; Electrocardiography ; Exposure ; Fibrosis ; Hematology ; Lead content ; Lead poisoning ; Markers ; Occupational exposure ; Regression analysis</subject><ispartof>Fresenius environmental bulletin, 2020-12, Vol.29 (12A), p.11501</ispartof><rights>Copyright Parlar Scientific Publications Dec 2020</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids></links><search><creatorcontrib>Karanfil, Mustafa</creatorcontrib><creatorcontrib>Gunduzoz, Meside</creatorcontrib><creatorcontrib>Karakurt, Murat</creatorcontrib><creatorcontrib>Arugarslan, Emre</creatorcontrib><creatorcontrib>Unal, Sefa</creatorcontrib><creatorcontrib>Akbuga, Kursat</creatorcontrib><creatorcontrib>Akdi, Ahmet</creatorcontrib><creatorcontrib>Erdol, Mehmet Akif</creatorcontrib><creatorcontrib>Yayla, Kadriye Gayretli</creatorcontrib><creatorcontrib>Ertem, Ahmet Goktug</creatorcontrib><creatorcontrib>Ozeke, Ozcan</creatorcontrib><creatorcontrib>Yayla, Cagri</creatorcontrib><title>FRAGMENTED QRS, AS A SURROGATE MARKER FOR MYOCARDIAL FIBROSIS, IS ASSOCIATED WITH HIGH BLOOD LEAD LEVELS</title><title>Fresenius environmental bulletin</title><description>Lead exposure is a serious environmental problem and associated with serious health prob- lems. Blood lead levels should be measured especially in lead exposed workers. Lead exposure could cause myocardial fibrosis and scar in cardiac tissue. Fragmented QRS (fQRS) is an easy to detect electrocardiography (ECG) finding and a predictor of myocardial scar. In this study we aimed to investigate the association of fQRS and lead exposure One hundred and fourty five occupationally lead exposed male workers with high blood lead levels and 158 male workers with normal blood lead levels are retrospectively evaluated. Hematological, echocardiography and ECG findings were compared. Workers with high blood lead level had significantly higher fQRS than workers with normal blood lead levels (13.8%, 4.4%, respectively, p: 0.004) In regression analysis, blood lead level is associated with fQRS (1.026( 1.011 -1.041), p=0.001). In this study, we found that workers with high blood lead levels has higher fQRS compared with workers with normal blood lead levels. fQRS could be a surrogated marker for suspicion for high blood lead. Further prospective and randomized trials is needed for this relationship.</description><subject>Blood</subject><subject>Blood levels</subject><subject>Echocardiography</subject><subject>EKG</subject><subject>Electrocardiography</subject><subject>Exposure</subject><subject>Fibrosis</subject><subject>Hematology</subject><subject>Lead content</subject><subject>Lead poisoning</subject><subject>Markers</subject><subject>Occupational exposure</subject><subject>Regression analysis</subject><issn>1018-4619</issn><issn>1610-2304</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNotTV1LwzAALKLgmPsPAV8t5KNJ28esS9tgajDpFJ9G0jbIEDfX7f-bofdwd3DH3U2yQAzBFBOY3UYPUZFmDJX3yWqe9zCC4Rwzskg-a8ObTrz0YgNejX0C3AIO7NYY3fBegI6bZ2FArQ3oPnTFzUZyBWq5NtrKWJexbq2uJL8uvMu-Ba1sWrBWWm-AEvxKb0LZh-QuuK95Wv3rMtnWoq_aVOlGVlylR1SQc-r8RL3PaeFDid0wjBSVOJTQUeLCiBlkPkw0G5wfkcdsgATRGJZ4hNShIZBl8vi3ezwdfi7TfN7tD5fTd7zc4azEOcwpoeQXvktLkg</recordid><startdate>20201201</startdate><enddate>20201201</enddate><creator>Karanfil, Mustafa</creator><creator>Gunduzoz, Meside</creator><creator>Karakurt, Murat</creator><creator>Arugarslan, Emre</creator><creator>Unal, Sefa</creator><creator>Akbuga, Kursat</creator><creator>Akdi, Ahmet</creator><creator>Erdol, Mehmet Akif</creator><creator>Yayla, Kadriye Gayretli</creator><creator>Ertem, Ahmet Goktug</creator><creator>Ozeke, Ozcan</creator><creator>Yayla, Cagri</creator><general>Parlar Scientific Publications</general><scope>7ST</scope><scope>7T7</scope><scope>7U7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope><scope>SOI</scope></search><sort><creationdate>20201201</creationdate><title>FRAGMENTED QRS, AS A SURROGATE MARKER FOR MYOCARDIAL FIBROSIS, IS ASSOCIATED WITH HIGH BLOOD LEAD LEVELS</title><author>Karanfil, Mustafa ; Gunduzoz, Meside ; Karakurt, Murat ; Arugarslan, Emre ; Unal, Sefa ; Akbuga, Kursat ; Akdi, Ahmet ; Erdol, Mehmet Akif ; Yayla, Kadriye Gayretli ; Ertem, Ahmet Goktug ; Ozeke, Ozcan ; Yayla, Cagri</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p183t-abe5bb758bf92accd5192f90a53afd2606bfe54cabd1b26c03150a592d05a1cf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Blood</topic><topic>Blood levels</topic><topic>Echocardiography</topic><topic>EKG</topic><topic>Electrocardiography</topic><topic>Exposure</topic><topic>Fibrosis</topic><topic>Hematology</topic><topic>Lead content</topic><topic>Lead poisoning</topic><topic>Markers</topic><topic>Occupational exposure</topic><topic>Regression analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Karanfil, Mustafa</creatorcontrib><creatorcontrib>Gunduzoz, Meside</creatorcontrib><creatorcontrib>Karakurt, Murat</creatorcontrib><creatorcontrib>Arugarslan, Emre</creatorcontrib><creatorcontrib>Unal, Sefa</creatorcontrib><creatorcontrib>Akbuga, Kursat</creatorcontrib><creatorcontrib>Akdi, Ahmet</creatorcontrib><creatorcontrib>Erdol, Mehmet Akif</creatorcontrib><creatorcontrib>Yayla, Kadriye Gayretli</creatorcontrib><creatorcontrib>Ertem, Ahmet Goktug</creatorcontrib><creatorcontrib>Ozeke, Ozcan</creatorcontrib><creatorcontrib>Yayla, Cagri</creatorcontrib><collection>Environment Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Toxicology Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environment Abstracts</collection><jtitle>Fresenius environmental bulletin</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Karanfil, Mustafa</au><au>Gunduzoz, Meside</au><au>Karakurt, Murat</au><au>Arugarslan, Emre</au><au>Unal, Sefa</au><au>Akbuga, Kursat</au><au>Akdi, Ahmet</au><au>Erdol, Mehmet Akif</au><au>Yayla, Kadriye Gayretli</au><au>Ertem, Ahmet Goktug</au><au>Ozeke, Ozcan</au><au>Yayla, Cagri</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>FRAGMENTED QRS, AS A SURROGATE MARKER FOR MYOCARDIAL FIBROSIS, IS ASSOCIATED WITH HIGH BLOOD LEAD LEVELS</atitle><jtitle>Fresenius environmental bulletin</jtitle><date>2020-12-01</date><risdate>2020</risdate><volume>29</volume><issue>12A</issue><spage>11501</spage><pages>11501-</pages><issn>1018-4619</issn><eissn>1610-2304</eissn><abstract>Lead exposure is a serious environmental problem and associated with serious health prob- lems. Blood lead levels should be measured especially in lead exposed workers. Lead exposure could cause myocardial fibrosis and scar in cardiac tissue. Fragmented QRS (fQRS) is an easy to detect electrocardiography (ECG) finding and a predictor of myocardial scar. In this study we aimed to investigate the association of fQRS and lead exposure One hundred and fourty five occupationally lead exposed male workers with high blood lead levels and 158 male workers with normal blood lead levels are retrospectively evaluated. Hematological, echocardiography and ECG findings were compared. Workers with high blood lead level had significantly higher fQRS than workers with normal blood lead levels (13.8%, 4.4%, respectively, p: 0.004) In regression analysis, blood lead level is associated with fQRS (1.026( 1.011 -1.041), p=0.001). In this study, we found that workers with high blood lead levels has higher fQRS compared with workers with normal blood lead levels. fQRS could be a surrogated marker for suspicion for high blood lead. Further prospective and randomized trials is needed for this relationship.</abstract><cop>Freising</cop><pub>Parlar Scientific Publications</pub></addata></record> |
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| ispartof | Fresenius environmental bulletin, 2020-12, Vol.29 (12A), p.11501 |
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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Blood Blood levels Echocardiography EKG Electrocardiography Exposure Fibrosis Hematology Lead content Lead poisoning Markers Occupational exposure Regression analysis |
| title | FRAGMENTED QRS, AS A SURROGATE MARKER FOR MYOCARDIAL FIBROSIS, IS ASSOCIATED WITH HIGH BLOOD LEAD LEVELS |
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