Ultrasound Controlled Anti‐Inflammatory Polarization of Platelet Decorated Microglia for Targeted Ischemic Stroke Therapy

Stroke is a lethal cerebral disease with severe sequelae and high mortality. Microglia, the main immune cell in the cerebrum, possess therapeutic potential for strokes as its specific anti‐inflammatory phenotype can reduce inflammation and promote neuron regeneration. However, the on‐demand anti‐inf...

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Veröffentlicht in:	Angewandte Chemie 2021-03, Vol.133 (10), p.5143-5150
Hauptverfasser:	Li, Yujie, Teng, Xucong, Yang, Chunrong, Wang, Yongji, Wang, Lingxiao, Dai, Yicong, Sun, Hua, Li, Jinghong
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis cell polarization Cerebrum Chemistry Complications Immune system Inflammation Irradiation Ischemia ischemic stroke Membrane fusion Microglia nanotechnology Neurogenesis Neurological diseases Phenotypes Platelets Polarization Radiation Recovery Recovery of function Regeneration Stroke Ultrasonic imaging Ultrasound
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