Skincare Products as Sources of Mutagenic Exposure to Infants: An Imperative Study Using a Battery of Microbial Bioassays
Infant skin is highly absorptive and sensitive to exposure from external agents (microbes, toxicants, heat, cold, etc.). Many specialized infant skincare products are currently commercially available. Although the manufacturers claim that their products are mild enough to suit the infant skin, these...
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| Veröffentlicht in: | Archives of environmental contamination and toxicology 2021-02, Vol.80 (2), p.499-506 |
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| creator | Nepalia, Amrita Singh, Anuradha Mathur, Nupur Kamath, Rajashree Pareek, Smita Agarwal, Maithili |
| description | Infant skin is highly absorptive and sensitive to exposure from external agents (microbes, toxicants, heat, cold, etc.). Many specialized infant skincare products are currently commercially available. Although the manufacturers claim that their products are mild enough to suit the infant skin, these products need to be studied for their safety. Using animal models to examine the safety of the ever-increasing number of skincare products is not economically or logistically feasible. To overcome this problem, we suggest using a battery of microbial bioassays as a robust system for monitoring the mutagenic potential of skincare products. We picked popular infant skincare products from the Indian market and assessed them by using a battery of three microbial mutagenicity bioassays. Most of them showed significant and reproducible mutagenic potential. Our study results raise concerns about regular use of infant products and emphasize the need to enforce strict regulations for the manufacturing and safety assessment of infant products. |
| doi_str_mv | 10.1007/s00244-021-00814-6 |
| format | Article |
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Many specialized infant skincare products are currently commercially available. Although the manufacturers claim that their products are mild enough to suit the infant skin, these products need to be studied for their safety. Using animal models to examine the safety of the ever-increasing number of skincare products is not economically or logistically feasible. To overcome this problem, we suggest using a battery of microbial bioassays as a robust system for monitoring the mutagenic potential of skincare products. We picked popular infant skincare products from the Indian market and assessed them by using a battery of three microbial mutagenicity bioassays. Most of them showed significant and reproducible mutagenic potential. 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Many specialized infant skincare products are currently commercially available. Although the manufacturers claim that their products are mild enough to suit the infant skin, these products need to be studied for their safety. Using animal models to examine the safety of the ever-increasing number of skincare products is not economically or logistically feasible. To overcome this problem, we suggest using a battery of microbial bioassays as a robust system for monitoring the mutagenic potential of skincare products. We picked popular infant skincare products from the Indian market and assessed them by using a battery of three microbial mutagenicity bioassays. Most of them showed significant and reproducible mutagenic potential. 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| ispartof | Archives of environmental contamination and toxicology, 2021-02, Vol.80 (2), p.499-506 |
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| subjects | Absorptivity Animal models Animals Bioassays Biological Assay Cosmetics - toxicity Earth and Environmental Science Ecotoxicology Environment Environmental Chemistry Environmental Exposure - statistics & numerical data Environmental Health Humans Industrial safety Infant Infants Microorganisms Models, Animal Monitoring/Environmental Analysis Mutagenicity Mutagens - toxicity Pollution Product safety Safety Skin Care - methods Skin Tests Soil Science & Conservation Toxicants |
| title | Skincare Products as Sources of Mutagenic Exposure to Infants: An Imperative Study Using a Battery of Microbial Bioassays |
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