Review of the Pharmacokinetics and Pharmacodynamics of Intravenous Busulfan in Paediatric Patients

We aimed to review the pharmacokinetics (PK) of intravenous busulfan in paediatric patients, identify covariate factors influencing exposure, investigate evidence of changes in PK behaviour over time, and correlate exposure with efficacy and toxicity outcomes. A literature review was undertaken of o...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical pharmacokinetics 2021, Vol.60 (1), p.17-51
Hauptverfasser:	Lawson, Rachael, Staatz, Christine E., Fraser, Christopher J., Hennig, Stefanie
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Clinical outcomes Drug dosages Enzymes Internal Medicine Literature reviews Medicine Medicine & Public Health Metabolism Metabolites Mortality Patients Pediatrics Pharmacodynamics Pharmacokinetics Pharmacology/Toxicology Pharmacotherapy Population Review Article
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!