Label-Free Detection of C–T Mutations by Surface-Enhanced Raman Spectroscopy Using Thiosulfate-Modified Nanoparticles

Recent developments in molecular spectroscopy have widened the scope of surface-enhanced Raman spectroscopy (SERS) for detection of nucleic acids. In order to solve the interference of impurity signals in SERS analysis that hamper the reliable detection of DNA, Ag nanoparticles modified with thiosul...

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Veröffentlicht in:	Analytical chemistry (Washington) 2021-02, Vol.93 (4), p.1951-1956
Hauptverfasser:	Zeng, Jiayu, Dong, Meiyu, Zhu, Bixue, Gao, Xin, Chen, Dongmei, Li, Yang
Format:	Artikel
Sprache:	eng
Schlagworte:	Aqueous solutions Base stacking Calcium Calcium ions Chemistry Citric acid Deoxyribonucleic acid DNA DNA - chemistry DNA sequencing Genetic analysis Genetic screening Ions Metal Nanoparticles - chemistry Molecular spectroscopy Mutation Nanoparticles Nucleic acids Raman spectroscopy Silver Silver - chemistry Spectroscopy Spectrum analysis Spectrum Analysis, Raman - methods Thiosulfate Thiosulfates Thiosulfates - chemistry
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