A human cell polarity protein Lgl2 regulates influenza A virus nucleoprotein exportation from nucleus in MDCK cells

In this study, the regulatory effect of the overexpression of polarity protein Lgl2 on the nuclear export of influenza A virus nucleoprotein in infected cells was investigated. A stable Tet-Off inducible MDCK cell line expressing a fusion protein comprising Lgl2 and an enhanced yellow fluorescent pr...

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Veröffentlicht in:	Journal of biosciences 2020-12, Vol.45 (1), Article 67
Hauptverfasser:	Liu, Jing, Wang, Haiying, Fang, Mengdan, Chen, Xuexin, Zeng, Xiaobo
Format:	Artikel
Sprache:	eng
Schlagworte:	Active Transport, Cell Nucleus - genetics Animals Bacterial Proteins - genetics Bacterial Proteins - metabolism Biology Biomedical and Life Sciences Biomedicine Cell Biology Cell fusion Cell Nucleus - genetics Cell Nucleus - metabolism Cell Nucleus - virology Cell Polarity Cells Claudin-1 - genetics Claudin-1 - metabolism Cytoskeletal Proteins - genetics Cytoskeletal Proteins - metabolism DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Dogs Exo-a-sialidase Fluorescence Fusion protein Gene Expression Regulation Host-Pathogen Interactions - genetics Humans Immunofluorescence Influenza Influenza A Influenza A Virus, H1N1 Subtype - genetics Influenza A Virus, H1N1 Subtype - metabolism Influenza A Virus, H3N2 Subtype - genetics Influenza A Virus, H3N2 Subtype - metabolism Life Sciences Life Sciences & Biomedicine Life Sciences & Biomedicine - Other Topics Luminescent Proteins - genetics Luminescent Proteins - metabolism Madin Darby Canine Kidney Cells Microbiology Nuclear transport Nuclei (cytology) Nucleocapsid Proteins - biosynthesis Nucleocapsid Proteins - genetics Plant Sciences Plasmids - chemistry Plasmids - metabolism Polarity Proteins Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Science & Technology Signal Transduction Transfection Transgenes Transport Virus Replication Viruses Yellow fluorescent protein Zoology
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