RETRACTED ARTICLE: Efficacy of favipiravir in COVID-19 treatment: a multi-center randomized study

No specific antiviral drugs have been approved for the treatment of COVID-19. This study aimed to evaluate the efficacy of favipiravir in treatment of COVID-19. This was a multicenter randomized controlled study including 96 patients with COVID- 19 who were randomly assigned into a chloroquine (CQ)...

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Veröffentlicht in:Archives of virology 2021-03, Vol.166 (3), p.949-954
Hauptverfasser: Dabbous, Hany M., Abd-Elsalam, Sherief, El-Sayed, Manal H., Sherief, Ahmed F., Ebeid, Fatma F. S., El Ghafar, Mohamed Samir Abd, Soliman, Shaimaa, Elbahnasawy, Mohamed, Badawi, Rehab, Tageldin, Mohamed Awad
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Sprache:eng
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Zusammenfassung:No specific antiviral drugs have been approved for the treatment of COVID-19. This study aimed to evaluate the efficacy of favipiravir in treatment of COVID-19. This was a multicenter randomized controlled study including 96 patients with COVID- 19 who were randomly assigned into a chloroquine (CQ) group and a favipiravir group. None of the patients in the favipiravir group needed mechanical ventilation ( p = 0.129). One patient (2.3%) in the favipiravir group and two patients (4.2%) in the CQ group died ( p = 1.00). Favipiravir is a promising drug for COVID-19 that decreases the hospital stay and the need for mechanical ventilation. ClinicalTrials.gov Identifier NCT04351295.
ISSN:0304-8608
1432-8798
DOI:10.1007/s00705-021-04956-9