Toward Ratiometric Detection of NAD(P)H Quinone Oxidoreductase-1: Benzocoumarin-Based Fluorescent Probes

[Display omitted] •A rational approach of mismatched orbital energies to develop ratiometric probes in case they contain a fluorescence quenching substrate such as a quinone.•One of two new probes responded fast (10 min) to NQO1 with ratiometric signal changes.•Both the probes enabled fluorescence i...

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