Investigation of nanoformulation and incorporation potential of radiolabeled curcumin using HeLa and MDAH-2774 cells
Nowadays plant origin compounds with anti-cancer properties come into prominence, among them is curcumin (CUR) with a remarkable anti-cancer activity against various cancers. CUR was nanoformulated (CUR-PLGA) by the polymer based poly(lactic- co -glycolic acid) (PLGA) and both CUR and CUR-PLGA were...
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| Veröffentlicht in: | Journal of radioanalytical and nuclear chemistry 2021, Vol.327 (1), p.299-305 |
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| container_title | Journal of radioanalytical and nuclear chemistry |
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| creator | Gokulu, Sevki Goksun Yurt Kilcar, Ayfer Bilgi, Ahmet Karatay, Kadriye Busra Yildirim, Nuri Kayas, Cansu Biber Muftuler, Fazilet Zumrut Terek, Mustafa Cosan |
| description | Nowadays plant origin compounds with anti-cancer properties come into prominence, among them is curcumin (CUR) with a remarkable anti-cancer activity against various cancers. CUR was nanoformulated (CUR-PLGA) by the polymer based poly(lactic-
co
-glycolic acid) (PLGA) and both CUR and CUR-PLGA were radiolabeled with iodine-131 radionuclide for investigation of their in vitro behaviour on Human cervix adenocarcinoma (HeLa) and Ovarian endometrioid adenocarcinoma (MDAH-2774) cell lines. The newly described radiolabeled CUR and CUR-PLGA may be initiative discovery of novel potential imaging and therapeutic agents. |
| doi_str_mv | 10.1007/s10967-020-07509-7 |
| format | Article |
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The newly described radiolabeled CUR and CUR-PLGA may be initiative discovery of novel potential imaging and therapeutic agents.</description><subject>Anticancer properties</subject><subject>Chemical compounds</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Diagnostic Radiology</subject><subject>Ethylenediaminetetraacetic acid</subject><subject>Glycolic acid</subject><subject>Hadrons</subject><subject>Heavy Ions</subject><subject>Inorganic Chemistry</subject><subject>Investigations</subject><subject>Iodine 131</subject><subject>Iodine isotopes</subject><subject>Measurement</subject><subject>Nuclear Chemistry</subject><subject>Nuclear Physics</subject><subject>Pharmacology</subject><subject>Physical Chemistry</subject><subject>Radiation</subject><subject>Radioisotopes</subject><issn>0236-5731</issn><issn>1588-2780</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp9kU9LJDEQxYOs4Kz6BTw1eG6tdDqd5Di4u44w4mX3HDJJZYj0JGPSvbDffjO24E3qUPB4v_rDI-SGwh0FEPeFghpECx20IDioVpyRFeVStp2Q8I2soGNDywWjF-R7Ka8AoKRkKzI9xb9YprA3U0ixSb6JJiaf8mEeF8lE14RoUz6mvCjHNGGcghlP9mxcSKPZ4YiusXO28yHEZi4h7psNbs07__xjvamXiL6xOI7lipx7Mxa8_uiX5M-vn78fNu325fHpYb1tLeNyarkcBtsDpZ6hclKi23nWI2dOdqBElajrLXJrZH1Muo4phdYbTneS7_qeXZLbZe4xp7e5vqlf05xjXam7XiqgqlOiuu4W196MqEP0acrG1nJ4CDZF9KHq64HTQXIleQW6BbA5lZLR62MOB5P_aQr6FIde4tA1Dv0ehz5tYQtUqjnuMX_e8gX1HzHHjcM</recordid><startdate>2021</startdate><enddate>2021</enddate><creator>Gokulu, Sevki Goksun</creator><creator>Yurt Kilcar, Ayfer</creator><creator>Bilgi, Ahmet</creator><creator>Karatay, Kadriye Busra</creator><creator>Yildirim, Nuri</creator><creator>Kayas, Cansu</creator><creator>Biber Muftuler, Fazilet Zumrut</creator><creator>Terek, Mustafa Cosan</creator><general>Springer International Publishing</general><general>Springer</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope><orcidid>https://orcid.org/0000-0001-8184-9660</orcidid></search><sort><creationdate>2021</creationdate><title>Investigation of nanoformulation and incorporation potential of radiolabeled curcumin using HeLa and MDAH-2774 cells</title><author>Gokulu, Sevki Goksun ; Yurt Kilcar, Ayfer ; Bilgi, Ahmet ; Karatay, Kadriye Busra ; Yildirim, Nuri ; Kayas, Cansu ; Biber Muftuler, Fazilet Zumrut ; Terek, Mustafa Cosan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c358t-5866c4011f3e9d88edbf34e53d820979d81d4ce5ca87318d2399ecfa51b85b443</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Anticancer properties</topic><topic>Chemical compounds</topic><topic>Chemistry</topic><topic>Chemistry and Materials Science</topic><topic>Diagnostic Radiology</topic><topic>Ethylenediaminetetraacetic acid</topic><topic>Glycolic acid</topic><topic>Hadrons</topic><topic>Heavy Ions</topic><topic>Inorganic Chemistry</topic><topic>Investigations</topic><topic>Iodine 131</topic><topic>Iodine isotopes</topic><topic>Measurement</topic><topic>Nuclear Chemistry</topic><topic>Nuclear Physics</topic><topic>Pharmacology</topic><topic>Physical Chemistry</topic><topic>Radiation</topic><topic>Radioisotopes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gokulu, Sevki Goksun</creatorcontrib><creatorcontrib>Yurt Kilcar, Ayfer</creatorcontrib><creatorcontrib>Bilgi, Ahmet</creatorcontrib><creatorcontrib>Karatay, Kadriye Busra</creatorcontrib><creatorcontrib>Yildirim, Nuri</creatorcontrib><creatorcontrib>Kayas, Cansu</creatorcontrib><creatorcontrib>Biber Muftuler, Fazilet Zumrut</creatorcontrib><creatorcontrib>Terek, Mustafa Cosan</creatorcontrib><collection>CrossRef</collection><jtitle>Journal of radioanalytical and nuclear chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gokulu, Sevki Goksun</au><au>Yurt Kilcar, Ayfer</au><au>Bilgi, Ahmet</au><au>Karatay, Kadriye Busra</au><au>Yildirim, Nuri</au><au>Kayas, Cansu</au><au>Biber Muftuler, Fazilet Zumrut</au><au>Terek, Mustafa Cosan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Investigation of nanoformulation and incorporation potential of radiolabeled curcumin using HeLa and MDAH-2774 cells</atitle><jtitle>Journal of radioanalytical and nuclear chemistry</jtitle><stitle>J Radioanal Nucl Chem</stitle><date>2021</date><risdate>2021</risdate><volume>327</volume><issue>1</issue><spage>299</spage><epage>305</epage><pages>299-305</pages><issn>0236-5731</issn><eissn>1588-2780</eissn><abstract>Nowadays plant origin compounds with anti-cancer properties come into prominence, among them is curcumin (CUR) with a remarkable anti-cancer activity against various cancers. 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| ispartof | Journal of radioanalytical and nuclear chemistry, 2021, Vol.327 (1), p.299-305 |
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| subjects | Anticancer properties Chemical compounds Chemistry Chemistry and Materials Science Diagnostic Radiology Ethylenediaminetetraacetic acid Glycolic acid Hadrons Heavy Ions Inorganic Chemistry Investigations Iodine 131 Iodine isotopes Measurement Nuclear Chemistry Nuclear Physics Pharmacology Physical Chemistry Radiation Radioisotopes |
| title | Investigation of nanoformulation and incorporation potential of radiolabeled curcumin using HeLa and MDAH-2774 cells |
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