Streptozotocin induces brain glucose metabolic changes and alters glucose transporter expression in the Lobster cockroach; Nauphoeta cinerea (Blattodea: Blaberidae)

The development of new models to study diabetes in invertebrates is important to ensure adherence to the 3R’s principle and to expedite knowledge of the complex molecular events underlying glucose toxicity. Streptozotocin (STZ)—an alkylating and highly toxic agent that has tropism to mammalian beta...

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