Can Organophosphates and Carbamates Cause Synergisms by Inhibiting Esterases Responsible for Biotransformation of Pyrethroids?

Hydrolysis catalyzed by general esterases (GEs) is the most efficient route for hydrolyzation of pyrethroid insecticides. Organophosphate (OP) and carbamate (CB) insecticides are known to inhibit GEs in addition to acetylcholinesterase (AChE), which is their main target. We hypothesize that synergie...

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Veröffentlicht in:	Environmental science & technology 2021-02, Vol.55 (3), p.1585-1593
Hauptverfasser:	Cao, Yi, Ibáñez Navarro, Alberto, Perrella, Lucas, Cedergreen, Nina
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholinesterase Acetylcholinesterase - metabolism Aldicarb Animals Biocompatibility Biotransformation Carbamate pesticides Carbamates (tradename) Carbamates - toxicity Chlorpyrifos Cholinesterase Inhibitors Contaminants in Aquatic and Terrestrial Environments Cypermethrin Detoxification Diazinon Esterases Fungicides In vivo methods and tests Insecticides Insecticides - toxicity Organophosphates Organophosphates - toxicity Parathion Pesticides Pyrethrins - toxicity Pyrethroids Risk assessment Synergistic effect Toxicity
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