Urinary clusterin and cystatin B as biomarkers of tubular injury in dogs following envenomation by the European adder

Diagnosing acute kidney injury remains a challenge since the established renal biomarkers, serum creatinine (sCr) and symmetric dimethylarginine (SDMA) reflect glomerular function and not tubular injury. Sensitive tubular markers such as urinary clusterin (uClust) and cystatin B (uCysB) have been pr...

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Veröffentlicht in:	Research in veterinary science 2021-01, Vol.134, p.12-18
Hauptverfasser:	Gordin, E., Gordin, D., Viitanen, S., Szlosek, D., Coyne, M., Farace, G., Murphy, R., Quinn, J., Yerramilli, Ma, Yerramilli, Mu, Spillmann, T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute kidney injury Acute Kidney Injury - blood Acute Kidney Injury - diagnosis Acute Kidney Injury - urine Acute Kidney Injury - veterinary Animals Arginine - analogs & derivatives Arginine - blood Arginine - urine Biomarkers Biomarkers - blood Biomarkers - urine Canine Case-Control Studies Clusterin Clusterin - blood Clusterin - urine Cohort Studies Correlation analysis Creatinine Creatinine - urine Cystatin B - blood Cystatin B - urine Cystatins Dog Diseases - blood Dog Diseases - urine Dogs Envenomation European adder Female Injuries Kidney Function Tests Kidneys Laboratories Male Prospective Studies Proteins Retrospective Studies Snake Bites - complications Snake Bites - urine Snake Bites - veterinary Snakes Tubular biomarker Urine Venom Veterinary medicine Viperidae
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